Search for dissertations about: "thesis in bacteria genome"

Showing result 11 - 15 of 171 swedish dissertations containing the words thesis in bacteria genome.

  2. 11. Evolutionary Dynamics of Mutation and Gene Transfer in Bacteria

    Author : Peter A Lind; Dan I Andersson; J. Arjan G. M. de Visser; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; fitness cost; bacterial evolution; gene amplification; mutational biases; GC content; synonymous substitutions; horizontal gene transfer; experimental evolution; Bacteriology; Bakteriologi; Microbiology; Mikrobiologi; Genetics; Genetik; Biology; Biologi; Mikrobiologi; Microbiology;

    Abstract : The study of bacterial evolution is fundamental for addressing current problems of antibiotic resistance and emerging infectious diseases and lays a solid foundation for successful and rational design in biotechnology and synthetic biology. The main aim of this thesis is to test evolutionary hypotheses, largely based on theoretical considerations and sequence analysis, by designing scenarios in a laboratory setting to obtain experimental data. READ MORE

  4. 12. Comparative analysis of pathogen occurrence in wastewater : management strategies for barrier function and microbial control

    Author : Jakob Ottoson; Bengt Hultman; Roland Schertenleib; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; bacteria; parasites; treatment; Water engineering; Vattenteknik;

    Abstract : This project was initiated to fill knowledge gaps on the occurrence of pathogens in different streams of wastewater, e.g. greywater and domestic wastewater. READ MORE

  5. 13. Evolutionary Processes and Genome Dynamics in Host-Adapted Bacteria

    Author : Björn Nystedt; Siv Andersson; David Guttman; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; molecular evolution; pathogen; secretion system; Bartonella; Buchnera; Blochmannia; Helicobacter; Bioinformatics; Bioinformatik; Evolutionary Genetics; evolutionär genetik;

    Abstract : Many bacteria live in close association with other organisms such as plants and animals, with important implications for both health and disease. This thesis investigates bacteria that are well adapted to live inside an animal host, and describes the molecular evolutionary processes underlying host-adaptation, based on bacterial genome comparisons. READ MORE

  6. 14. It Takes Two to Tango : Bacterial heterogeneity and host cell features govern Salmonella infection

    Author : Viktor Ek; Mikael E. Sellin; Francisco García del Portillo; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Salmonella; swimming; swim pattern; targetting; virulence; invasion; host-pathogen interactions; epithelium; epithelial cells; macrophages; monocytes; monolayer; flagella; genome; genetic; barcoding; discreet-invasion; shape; morphology; antibiotics; persistence; Mikrobiologi; Microbiology;

    Abstract : Salmonella enterica serovar Typhimurium (S.Tm) causes enterocolitis with significant worldwide morbidity and mortality. The general aim of this thesis is to investigate variation in host cell invasion mechanisms used by S.Tm across different host cell contexts, as well as the influence of bacterial cell-cell heterogeneity on invasion-relevant S. READ MORE

  7. 15. Molecular mechanisms and biological consequences of the production of non-canonical D-amino acids in bacteria

    Author : Alena Aliashkevich; Felipe Cava; Fredrik Almqvist; Andrew J Roe; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Bacteria; cell wall; peptidoglycan; D-amino acids; LD-transpeptidase;

    Abstract : Most bacteria possess a vital net-like macromolecule – peptidoglycan (PG). PG encases bacteria around the cytoplasmic membrane to withstand the high internal turgor pressure and thereby protect the cell from bursting. In addition, PG is a major morphological determinant of bacteria being both required and sufficient to maintain cell shape. READ MORE