Search for dissertations about: "thesis in bacteria genome"

Showing result 6 - 10 of 171 swedish dissertations containing the words thesis in bacteria genome.

  2. 6. Hidden patterns that matter : statistical methods for analysis of DNA and RNA data

    Author : Therese Kellgren; Patrik Rydén; Sara Sjöstedt de Luna; Rebecka Jörnsten; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Genome; Next-generation sequence; statistics; microarrays; bacteria; antibiotic resistance; inherited diseases; Co-expression networks; centralization within subgroups;

    Abstract : Understanding how the genetic variations can affect characteristics and function of organisms can help researchers and medical doctors to detect genetic alterations that cause disease and reveal genes that causes antibiotic resistance. The opportunities and progress associated with such data come however with challenges related to statistical analysis. READ MORE

  4. 7. Evolution of streamlined genomes in ultra-small aquatic bacteria

    Author : Weizhou Zhao; Siv Andersson; Sandra L. Baldauf; Sarahi L Garcia; Karen Lloyd; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; streamlined genome; aquatic bacteria; single cell genomics; metagenomics; evolutionary genomics; salinity; Baltic Sea; Biologi med inriktning mot molekylär evolution; Biology with specialization in Molecular Evolution;

    Abstract : This thesis investigates the evolutionary processes of streamlined genomes from aquatic bacteria adapting to different salinities, using two groups of ultra-small aquatic bacteria (LD12 Alphaproteobacteria and acI Actinobacteria). Due to difficulties in obtaining pure cultures of these bacteria, culture-free approaches (single-cell genomics and metagenomics) were used to construct and compare genomes, and to study the mechanisms and selective forces of adaptation to freshwater, brackish, and marine ecosystems. READ MORE

  5. 8. Molecular evolutionary studies of genome degradation in bacteria

    Author : Jan O. Andersson; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Developmental biology; Utvecklingsbiologi; Developmental biology; Utvecklingsbiologi; molekylärbiologi; Molecular Biology;

    Abstract : The genus Rickettsia belongs to the α-proteobacteria and consists of obligate intracellular bacteria, which often are pathogenic for humans. All Rickettsia have small genomes, highly adapted to an intracellular lifestyle. READ MORE

  6. 9. Apoptosis induced by a human milk protein complex. Cellular and structural studies in tumour cells and bacteria

    Author : Anders Håkansson; immunologi och glykobiologi - MIG Avdelningen för mikrobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; serology; Immunology; nuclear uptake; caspases; mitochondria; S. pneumoniae; alpha-lactalbumin; milk; breast-feeding; Apoptosis; tumour cells; transplantation; Immunologi; serologi;

    Abstract : Human milk contains a vast array of bioactive molecules, with nutritional and protective functions. This thesis describes the effects of a human milk protein complex, MAL, on tumour cells and bacteria. During our studies on the anti-adhesive properties of human milk we observed that a milk fraction killed tumour cells. READ MORE

  7. 10. Bioremediation of Toxic Metals for Protecting Human Health and the Ecosystem

    Author : Aminur Rahman; Abul Mandal; Jana Jass; Björn Olsson; Pawel Kaszycki; Örebro universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Heavy Metals; Pollution; Accumulation; Remediation; Human Health; Bacteria; Genome Sequencing; de novo Assembly; Gene Prediction; Biology; Biologi; Bioteknik;

    Abstract : Heavy metal pollutants, discharged into the ecosystem as waste by anthropogenic activities, contaminate drinking water for millions of people and animals in many regions of the world. Long term exposure to these metals, leads to several lethal diseases like cancer, keratosis, gangrene, diabetes, cardio- vascular disorders, etc. READ MORE