Search for dissertations about: "thesis in ciprofloxacin"

Showing result 1 - 5 of 63 swedish dissertations containing the words thesis in ciprofloxacin.

  2. 1. Exploring the Ciprofloxacin Resistome

    Author : Linnéa Garoff; Diarmaid Hughes; Jesús Blázquez; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Antibiotic resistance; Experimental evolution; Ciprofloxacin; Escherichia coli; Mikrobiologi; Microbiology;

    Abstract : This thesis presents an exploration of the resistance evolution in Escherichia coli towards the antibiotic ciprofloxacin. High level ciprofloxacin resistance is typically acquired by an accumulation of mutations and plasmid borne genes reducing drug target binding, increasing drug efflux, and modifying the drug. READ MORE

  4. 2. Host-Pathogen Interactions in Pseudomonas aeruginosa Invasive and Respiratory Tract Infection

    Author : Magnus Paulsson; Malmö Klinisk mikrobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pseudomonas aeruginosa; vitronectin; Respiratory tract infections; Innate Immunity; outer membrane vesicles; outer membrane proteins; beta-lactamase; ciprofloxacin; combination treatment; bacteraemia; Complement escape;

    Abstract : Pseudomonas aeruginosa is an opportunistic bacterium that causes debilitating infections when the immune defence is compromised. It possesses an arsenal of virulence traits to colonize most compartments of the body and is often highly resistant against commonly used antimicrobial drugs. READ MORE

  5. 3. Constraints on up-regulation of drug efflux in the evolution of ciprofloxacin resistance

    Author : Lisa Praski Alzrigat; Diarmaid Hughes; Fernando Baquero; Uppsala universitet; []
    Keywords : ciprofloxacin; antibiotic resistance; drug efflux; bacterial fitness; marR; acrR; marA; experimental evolution; Mikrobiologi; Microbiology;

    Abstract : The crucial role of antibiotics in modern medicine, in curing infections and enabling advanced medical procedures, is being threatened by the increasing frequency of resistant bacteria. Better understanding of the forces selecting resistance mutations could help develop strategies to optimize the use of antibiotics and slow the spread of resistance. READ MORE

  6. 4. Host-parasite interaction in men with febrile urinary tract infection

    Author : Peter Ulleryd; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; urinary tract infection; fever; male; Escherichia coli; serotype; virulence; PSA; prostate; prostatitis; TRUS; urography; cystoscopy; treatment; ciprofloxacin;

    Abstract : In a retrospective study, Escherichia coli isolates from 88 men with symptomatic urinary tract infection (UTI) were analysed. A wide array of O:K:H serotypes commonly associated with acute pyelonephritis in women were identified. READ MORE

  7. 5. Mechanisms of resistance to ciprofloxacin in Neisseria gonorrhoeae

    Author : Emma Lindbäck; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Neisseria gonorrhoeae; ciprofloxacin; DNA-gyrase; topoisomerase IV; major outer membrane protein;

    Abstract : A few years ago, most strains of Neisseria gonorrhoeae were susceptible to ciprofloxacin, but after introduction as a first line therapy, resistant strains emerged. Ciprofloxacin inhibit two enzymes necessary for DNA replication. READ MORE