Search for dissertations about: "thesis in epigenetics"

Showing result 1 - 5 of 110 swedish dissertations containing the words thesis in epigenetics.

  2. 1. Networks in epigenetics

    Author : Kuljeet Sandhu; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Networks are ubiquitous. It is only recently, we started exploring what purpose they serve in real world. Biological research supposedly has, and will be, benefited most from the network science because of inherent complexity embedded in its multilayered organization. READ MORE

  4. 2. Epigenetic dysregulation in relation to psychiatric traits in adolescence and adulthood

    Author : Adrian Desai Boström; Helgi B. Schiöth; Daniel Nätt; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; methylome-wide; DNA methylation; hypersexual disorder; microRNA; oxytocin signaling; psychiatry; hsa-miR-4456; microRNA-4456; MIR4456; epigenetic dysregulation; microRNA expression; gene target prediction; epigenetics; suicide; suicide attempt; HPA axis; CRH gene; Epigenetics; Methylation; Adolescent depression; MIR4646; methylome-wide association study; Omega-3; mQTL analysis; GAD1; HDAC3; DAWBA;

    Abstract : Epigenetics has evolved into a key research focus in the field of psychiatry. DNA methylation is the most researched epigenetic mechanism. In paper I-III, 130 and 93 adolescents were randomly recruited at two separate intervals. READ MORE

  5. 3. Epigenetics in nasopharyngeal carcinoma

    Author : Di Sun; Karolinska Institutet; Karolinska Institutet; []
    Keywords : NPC; Methylation; TSG; EBV; LMP1; CDH13; RASSF2A; MMSP;

    Abstract : Nasopharyngeal carcinoma (NPC) shows a remarkably distinctive ethnic and geographic distribution among the world suggesting that genetic susceptibility backgrounds cooperate with the environmental risk factors in etiology of NPCs. Among the environmental factors, much attention has been focused on a well-documented association with Epstein-Barr virus (EBV), which can be detected in 100% undifferentiated NPCs. READ MORE

  6. 4. Selection in sperm and its consequences : Exploring haploid selection, ageing and epigenetic effects in sperm

    Author : Cosima Hermans Née Hotzy; Simone Immler; Göran Arnqvist; Mariana Wolfner; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; sperm; evolution; selection; haploid selection; epigenetics; sperm-mediated effects; trans-generational effects; sperm ageing; sperm senescence;

    Abstract : Sexually reproducing eukaryotes are typically going through a biphasic life cycle with a diploid and a haploid phase. Unlike in plants where selection on haploid pollen genotypes is well established, the possibility of selection occurring in animal sperm is currently not known. READ MORE

  7. 5. SOX11 in Mantle Cell Lymphoma - Novel Tools for Diagnostic, Prognostic and Functional Investigations

    Author : Lena Nordström; Institutionen för immunteknologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Antibodies; DNA methylation; Epigenetics; SOX11; Lymphoma;

    Abstract : The goal of biomarker discovery is to identify disease defining molecules, which could be used to improve early detection and/or to predict survival and response to treatment. This thesis is about the transcription factor SOX11, a protein discovered in the context of mantle cell lymphoma in 2008, which shows great potential to be used as a clinical relevant biomarker. READ MORE