Search for dissertations about: "thesis in hepatitis c liver fibrosis"

Showing result 1 - 5 of 16 swedish dissertations containing the words thesis in hepatitis c liver fibrosis.

  1. 1. Hepatitis C virus infection. Viral genotypes and factors promoting liver fibrosis

    Author : Johan Westin; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hepatitis C virus; genotypes; epidemiology; liver fibrosis; histology; scoring; prognosis; alcohol; liver steatosis;

    Abstract : Hepatitis C virus (HCV) is associated with chronic infection in a majority of infected individuals. Chronic hepatitis C may result in liver cirrhosis or hepatocellular cancer and is therefore considered a major health problem worldwide. READ MORE

  2. 2. Towards the elimination of hepatitis C : identifying the infected population, and remaining hepatitis C related risks after successful treatment

    Author : Charlotte Lybeck; Ann-Sofi Duberg; Soo Aleman; Scott Montgomery; Magnus Gottfredsson; Örebro universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HCV; HCC; epidemiology; MTCT; pregnancy; DAA; OCI;

    Abstract : Chronic Hepatitis C virus (HCV) infection can lead to liver fibrosis and cirrhosis with increased risk of hepatocellular carcinoma (HCC) and liver failure. The World Health Organisation (WHO) has set a goal to eliminate viral hepatitis as a global health threat by 2030. READ MORE

  3. 3. Studies on mechanisms in liver fibrosis

    Author : Nils Kinnman; Karolinska Institutet; Karolinska Institutet; []
    Keywords : bile duct epithelial cell; chernotaxis; cholestasis; cystic fibrosis; cystic fibrosis transmembrane conductance regulator; endothelin; hepatic stellate cell; hepatitis C virus; liver fibrosis; platelet-derived growth factor; platelet-derived growth factor receptor [beta]; smooth muscle [alpha]-actin; transforming growth factor- [beta]; tumor necrosis factor-[alpha];

    Abstract : The aim of the present study was to elucidate mechanisms involved in liver fibrogenesis, the wound healing response of the liver to chronic injury. A role for TNF-[alpha] and all three isoforms of TGF-[beta] in the pathogenesis of hepatitis C related liver disease was suggested by the finding of increased expression of TGF-[beta]1-3, latent TGF-[beta] binding protein (LTBP), and TNF-[alpha] by immunohistochemistry in areas of inflammation and fibrosis in liver tissue from untreated patients with hepatitis C. READ MORE

  4. 4. Hepatitis C virus. Aspects on natural history, antibody response, and viral quantification

    Author : Martin Lagging; Göteborgs universitet; []
    Keywords : Hepatitis C virus; nosocomial infection; pseudotyped virus; fibrosis; viral quantification;

    Abstract : Hepatitis C virus (HCV) is the major cause of parenterally transmitted non-A, non-B hepatitis, and is associated with chronic hepatitis, cirrhosis, and hepatocellular carcinoma. Despite the screening of blood products nosocomial spread of HCV continues to occur. READ MORE

  5. 5. Natural course and treatment outcome in hepatitis C recurrence after liver transplantation

    Author : Malin Ackefors; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Hepatitis C virus (HCV) infection post-liver transplantation (post-LT) is associated with an increased rate of fibrosis progression compared to non-transplanted patients. Thus, 25% of the recipients will progress to cirrhosis within 5 years after LT. READ MORE