Search for dissertations about: "thesis in immunology and drug disease"
Showing result 1 - 5 of 14 swedish dissertations containing the words thesis in immunology and drug disease.
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1. Interplay of human macrophages and Mycobacterium tuberculosis phenotypes
Abstract : Mycobacterium tuberculosis (Mtb) is the pathogen causing tuberculosis (TB), a disease most often affecting the lung. 1.5 million people die annually due to TB, mainly in low-income countries. READ MORE
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2. Immunosuppressive and metastasis-promoting matrisome proteins in pancreatic cancer : the role of galectin 4 and SERPINB5
Abstract : In Sweden 1200-1300 people are diagnosed with pancreatic ductal adenocarcinoma (PDAC) every year. Late diagnosis, together with poor treatment response and resistance to checkpoint inhibitor immunotherapy, contributes to the poor prognosis of the disease. READ MORE
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3. Molecular Mechanisms of Reward and Aversion
Abstract : Various molecular pathways in the brain shape our understanding of good and bad, as well as our motivation to seek and avoid such stimuli. This work evolves around how systemic inflammation causes aversion; and why general unpleasant states such as sickness, stress, pain and nausea are encoded by our brain as undesirable; and contrary to these questions, how drugs of abuse can subjugate the motivational neurocircuitry of the brain. READ MORE
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4. On dysregulated inflammation and airway host defense
Abstract : Acute respiratory distress syndrome (ARDS), chronic obstructive pulmonary disease (COPD), and cystic fibrosis (CF) are characterized by dysregulated inflammation of the airways. The increased influx of immune cells and the accumulation of cytokines lead to cell death, tissue destruction and impaired pulmonary function. READ MORE
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5. In Vitro Studies of Factors Potentially Affecting Plasmodium Falciparum Infection : (Heparin and Anti-P. falciparum Immune Responses)
Abstract : Plasmodium falciparum malaria is considered one of the major infectious diseases in humans, with regard to mortality and morbidity. Growing resistance of malaria to most anti-malaria drugs and of the Anopheles mosquitoes to insecticides have resulted in a global resurgence of the disease. READ MORE