Search for dissertations about: "thesis in lupus"
Showing result 1 - 5 of 176 swedish dissertations containing the words thesis in lupus.
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1. Immunological mechanisms in systemic autoimmunity : autoantibodies and chemokines in systemic lupus erythematosus and during treatment with TNF inhibitors in rheumatoid arthritis
Abstract : Background. Rheumatoid Arthritis (RA) is an autoimmune inflammatory disease that, without powerful treatment, may lead to irreversible joint damage. During the past decade, anti-cytokine therapy has become available, e.g. READ MORE
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2. Aspects on Immune Complex Handling and Complement Deficiency in Relation to Pathogenic Mechanisms in Systemic Lupus Erythematosus
Abstract : The autoimmune disease Systemic Lupus Erythematosus is associated with hereditary deficieny of early components from the classical pathway of complement activation, but not with deficiency of complement component C3 or of the alternative pathway components. The classical pathway is involved in elimination of pathological immune complexes from the circulation by transport via complement receptor type 1 (CR1). READ MORE
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3. Osteoporosis in SLE
Abstract : As the treatment of Systemic Lupus Erythematosus (SLE) has become more effective the focus has partly shifted from main concern of short term morbidity and survival to long term complications such as osteoporosis. The aims of this thesis were to a) determine prevalence and risk factors of osteoporosis and of b) vertebral fractures c) evaluate if adequate osteoporotic treatment was provided d) determine if resistin, an adipokine with proposed pro-inflammatory properties, was associated with markers of inflammation or bone mineral density (BMD) and to e) investigate patients self reported health related quality of life (HRQOL) and its relationship to disease variables and employment status in female SLE patients. READ MORE
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4. Apoptosis of Peripheral Blood Leukocytes in Systemic Lupus Erythematosus: Studies on Serum Induction and Complement-Dependent Clearance Mechanisms
Abstract : Systemic lupus erythematosus (SLE) is an autoimmune disease involving many organ systems. The cause is not known, but a complex combination of environmental and genetic factors seems to be involved. READ MORE
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5. Complement-dependent defence against bacterial infection. Studies in C2 deficiency
Abstract : The complement system is critically involved in defence against bacterial infection. C2 deficiency is, apart from mannan-binding lectin (MBL) deficiency, the most common homozygous complement deficiency among Caucasians. READ MORE