Search for dissertations about: "thesis in malaria immunology"

Showing result 1 - 5 of 38 swedish dissertations containing the words thesis in malaria immunology.

  2. 1. Novel immunization strategies and interethnic differences in response to malaria infection

    Author : Charles Arama; Marita Troye-Blomberg; Kai Matuschewski; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Malaria; Immunization; Ethnic groups; vaccines; immunologi; Immunology;

    Abstract : A better understanding of the role of antigen-presenting cells (APCs) in host resistance to malaria is essential to unravel the complex interactions between the host and the parasite. This would improve the design of malaria vaccines. READ MORE

  4. 2. Human genetic factors involved in immunity to Plasmodium falciparum infection

    Author : Manijeh Vafa Homann; Marita Troye-Blomberg; Marcel Hommel; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Plasmodium falciparum; Malaria; Immunity; Ethnic groups; Mali; Senegal; Genetic factors; IL-4; IL-10; Polymorphism; MOI; RBC variants; Immunology; Immunologi; immunologi; Immunology;

    Abstract : This study investigated the associations between IL-4 -590 C/T and IL-10 -1087 A/G polymorphisms and malariometric indexes in the Fulani and the Dogon ethnic groups living in sympatry in Mali and differing in susceptibility to malaria. The correlations between antibodies level and parasitological data as well as splenomegaly were assessed. READ MORE

  5. 3. Vaccine development strategies applied to the Plasmodium falciparum malaria antigen 332

    Author : Nina-Maria Vasconcelos; Klavs Berzins; Matti Sällberg; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; malaria; sub-unit vaccines; immunogenicity; antibody response; antigen Pf332; Immunology; Immunologi;

    Abstract : Malaria is one of the major infectious diseases in the world with regard to mortality and morbidity, and the development of a vaccine against the malaria parasite Plasmodium falciparum is considered of high priority. The aim of the work presented in this thesis was to develop and characterize recombinant vaccine constructs based on the P. READ MORE

  6. 4. Single nucleotide polymorphisms related to immune responses in Plasmodium falciparum malaria

    Author : Amre Nasr; Klavs Berzins; Marita Troye-Blomberg; Gehad ElGhazali; Thor Theander; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; FcγRIIa-R H131; CRP genotypes; GM KM allotypes; IgG; and malaria; Sudan; Immunology; Immunologi; immunologi; Immunology;

    Abstract : The current research is directed towards dissection of host genetic factors involved in host immune response and the malaria disease outcome. A possible association between FcγRIIa polymorphism and anti-malarial antibody (A.M.A) responses were investigated in Sudanese patients in relation to clinical outcome of falciparum malaria. READ MORE

  7. 5. Dissecting the complexity of human susceptibility to Plasmodium falciparum malaria: genetic approaches

    Author : Valentina D Mangano; Marita Troye-Blomberg; Marta Alarcon; Stockholms universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; immunology; genetics; malaria; Immunology; Immunologi; immunologi; Immunology;

    Abstract : There are many aspects of the immunology of P. falciparum infection that are not understood. Genetic approaches are of great value for dissecting the complexity of immune responses to malaria in natura by providing new insights into molecular interactions between the parasite and the host. READ MORE