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Showing result 1 - 5 of 22 swedish dissertations matching the above criteria.

2. 1. Malaria and relapsing fever Borrelia : interactions and potential therapy

   Author : Jenny Lundqvist; Cathrine Persson; Antonio Barragan; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Malaria; Plasmodium; relapsing fever; Borrelia; persistent; concomitant infections; polyamines; Molecular biology; Molekylärbiologi; Microbiology; immunology; infectious diseases; Mikrobiologi; immunologi; infektionssjukdomar; molekylär bioteknik inst f molekylärbiologi ; molecular biotechnology dept of molecular biology ; Infectious Diseases; infektionssjukdomar;

   Abstract : Infectious diseases such as malaria and relapsing fever borreliosis (RF), cause severe human mortality and morbidity in developing countries. Malaria, caused by Plasmodium spp. parasites, is estimated by the World Health Organization to cause 1.5-2. READ MORE

4. 2. Uncovering the genetics underlying host-parasite interactions during Plasmodium falciparum malaria transmission

   Author : Mubasher Mohammed; Johan Ankarklev; David Serre; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Malaria; Plasmodium falciparum; Genomics; single-cell RNA-seq; Parasite cell fate; Anopheles gambiae; ApiAP2 transcription factors; driver genes; computational biology; molekylär biovetenskap; Molecular Bioscience;

   Abstract : In eukaryotes, cellular differentiation is often orchestrated by programmed arrays of activation and repression of genes underlying the specific phenotypes of cell-types. To complete its life cycle, the single-celled Apicomplexan parasite Plasmodium falciparum, the most deadly of the human malaria parasites, must repeatedly differentiate and convert into unique cell types that can exploit niches within their human and mosquito hosts. READ MORE

5. 3. Identification of bacteria associated with malaria mosquitoes - Their characterisation and potential use

   Author : Jenny Lindh; Ingrid Faye; Marcelo Jacobs-Lorena; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Malaria; mosquito; Anopheles; bacteria; paratransgenics; semiochemicals; Molecular biology; Molekylärbiologi; molekylärgenetik; Molecular Genetics;

   Abstract : The use of transformed bacteria to stop or kill disease-causing agents in the gut of vector insects is called paratransgenics. Two of the major steps in creating a paratransgenic Anopheles mosquito, unable to spread the Plasmodium parasites that cause malaria, are to find a bacterium suitable for the purpose and a way to introduce the transformed bacterium into mosquitoes in the field. READ MORE

6. 4. Decoding the language of transmission among vector-pathogen-host

   Author : Melika Hajkazemian; S. Noushin Emami; Richard Hopkins; Stockholms universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Vector-borne disease; Malaria; Anopheles; Plasmodium falciparum; Zika; Aedes; Vector control strategy; molekylär biovetenskap; Molecular Bioscience;

   Abstract : Vector-borne diseases account for over 17 percent of all infectious diseases and lead to more than 700,000 mortalities annually. Importantly, there is a complex interaction between infectious organisms and their host. READ MORE

7. 5. Structure-Assisted Design of Drugs Towards HIV-1 and Malaria Targets : Applied on Reverse Transcriptase and Protease from HIV-1 and Plasmepsin II from Plasmodium falciparum

   Author : Jimmy Lindberg; Torsten Unge; Alexander Wlodawer; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; X-ray crystallography; Drug design; HIV-1; Malaria; Molekylärbiologi; Molecular biology; Molekylärbiologi;

   Abstract : Globally of today, acquired immunodeficiency syndrome (AIDS) and malaria are two of the most threatening diseases known to mankind. The World Health Organization estimated that AIDS and malaria together claimed nearly 4 million lives in 2003 and many more were infected by the causative agent human immunodeficiency virus (HIV) and the Plasmodium falciparum (P. READ MORE