Search for dissertations about: "thesis in medical microbiology hiv aids"
Showing result 1 - 5 of 13 swedish dissertations containing the words thesis in medical microbiology hiv aids.
-
1. Effects of galectins and antibodies in HIV infection; Novel Assays
Abstract : The high variability of the HIV envelope glycoproteins (Env), and their heavy glycan coating, contributes to the limited host immune control. Still, broadly neutralizing antibodies (bnAbs) are found in some chronically infected HIV-infected individuals, which has spurred the research on antibody-based vaccines. READ MORE
-
2. HIV-1 envelope protein gp120. Glycovirology of the V3 loop
Abstract : The human immunodeficiency virus type 1 (HIV-1) infection usually is lethal as a consequence of the acquired immunodeficiency syndrome (AIDS). HIV-1 is an enveloped virus and the trimeric envelope glycoprotein complex, gp120/gp41, is responsible for binding of the virus both to the primary cellular receptor CD4 and the coreceptors, CXCR4 and CCR5. READ MORE
-
3. On cerebrospinal fluid markers of HIV-1 infection
Abstract : HIV-1 infects the central nervous system early in the course of infection and neurological complications are common in HIV-1-infected individuals. Approximately 20% of individuals with acquired immunodeficiency syndrome (AIDS) not treated with antiretroviral therapy develop a subcortical dementia, AIDS dementia complex (ADC). READ MORE
-
4. Studies on Potency and breadth of HIV-1, HIV-2 and SIV neutralizing antibody responses
Abstract : Even though the relative contribution of neutralizing antibodies (Nab) to prevent progression to AIDS during HIV-1 infection is still unclear, the induction of broadly NAb directed against HIV-1 through vaccination is considered to represent an important goal for the development of HIV-1 vaccines. Factors contributing to the induction of NAb may include the strength and duration of antigenic stimulation, the preservation of CD4+ T and B cells, the conformation of the HIV-1 envelope glycoprotein complex (Env), and the evolution of Env during infection. READ MORE
-
5. Virus tropism and neutralization response in SIV infection
Abstract : Simian immunodeficiency virus (SIV) infections in macaques are commonly used as models to study the pathogenesis of human immunodeficiency virus (HIV). Both SIV and HIV normally use the CD4 receptor and an additional coreceptor for cell entry. The most common coreceptors used by HIV are CCR5 and CXCR4. READ MORE