Search for dissertations about: "thesis in ovarian cancer pathology"

Showing result 1 - 5 of 8 swedish dissertations containing the words thesis in ovarian cancer pathology.

2. 1. Advanced Ovarian Cancer. A multimodal diagnostic approach to predict outcome

   Author : Mihaela Asp; Lund Obstetrik och gynekologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Advanced ovarian cancer; multidisciplinary; tru-cut biopsy; frozen section; peritoneal cancer index; CT; primary debulking surgery; cytoreductive surgery; survival;

   Abstract : Primary debulking surgery (PDS) followed by platinum-based postoperative chemotherapy isthe standard of care for advanced ovarian cancer (AOC). Absence of macroscopic residualdisease after debulking surgery is the strongest prognostic factor achieved by surgery. READ MORE

4. 2. Pelvic inflammatory disease and epithelial ovarian tumors

   Author : Sarah Jonsson; Annika Idahl; Eva Lundin; Håkan Jonsson; Christer Borgfeldt; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Abstract : Background: Epithelial ovarian cancer and borderline ovarian tumors consist of several histotypes in which high-grade serous carcinoma is the most common. The majority of epithelial ovarian tumors are considered to originate in the fimbriated end of the fallopian tubes. What initiates these tumors is far from completely understood. READ MORE

5. 3. Aspects of Gene Expression Profiling in Disease and Health

   Author : Julia Bergman; Fredrik Pontén; Lars Akslen; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cancer; biomarkers; differential diagnostics; immunohistochemistry; transcriptomics; protein profiling; adrenal gland.; Pathology; Patologi;

   Abstract : The aim of this thesis is to in various ways explore protein expression in human normal tissue and in cancer and to apply that knowledge in biomarker discovery.In Paper I the prognostic significance of RNA-binding motif protein 3 (RBM3) is explored in malignant melanoma. READ MORE

6. 4. Hormone concentrations during pregnancy and maternal risk of epithelial ovarian cancer

   Author : Helena Schock; Eva Lundin; Annika Idahl; Renée Turzanski Fortner; Anne Zeleniuch-Jacquotte; Shelley S Tworoger; Umeå universitet; []
   Keywords : LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; epithelial ovarian cancer; sex steroid hormones; IGF-I; placental GH; AMH; pregnancy; prospective study; patologi; Pathology;

   Abstract : Background: The aim of this thesis was to study the relationship of pre-diagnostic circulating concentrations of sex steroid hormones (androgens, estradiol, 17-hydroxyprogesterone, and progesterone), growth factors (insulin-like growth factor-I (IGF-I), placental growth hormone (GH)), sex hormone binding globulin (SHBG), and anti-Müllerian hormone (AMH) with risk of epithelial ovarian cancer (EOC) overall, and by tumor invasiveness and histology. A longitudinal study was used to assess patterns of hormonal changes during a single pregnancy, and in two consecutive pregnancies. READ MORE

7. 5. Significance of Wilms’ tumor gene 1 as a biomarker in acute leukemia and solid tumors

   Author : Charlotta Andersson; Eva Lundin; Aihong Li; Andreas Jonsson; Xingru Li; David M. Loeb; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Wilms’ tumor gene 1; biomarker; leukemia; renal cell carcinoma; ovarian carcinoma; Clinical Chemistry; klinisk kemi; patologi; Pathology;

   Abstract : Wilms’ tumor gene 1 (WT1) is a zinc finger transcriptional regulator with crucial functions in embryonic development. Originally WT1 was described as a tumor suppressor gene, but later studies have shown oncogenic properties of WT1 in a variety of tumors. Because of its dual functions in tumorigenesis, WT1 has been described as a chameleon gene. READ MORE