Search for dissertations about: "thesis in pathogenesis of type 2 diabetes mellitus"

Showing result 1 - 5 of 23 swedish dissertations containing the words thesis in pathogenesis of type 2 diabetes mellitus.

2. 1. Genetic and immunological risk factors of gestational diabetes mellitus

   Author : Nael Shaat; diabetes och endokrinologi Genomik; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; GDM; Association; genetics; gestational diabetes mellitus metabolic syndrome; MODY; type 1 diabetes; risk factors; type 2 diabetes; Endocrinology; diabetology; secreting systems; autoimmunity; Endokrinologi; sekretion; diabetologi;

   Abstract : Gestational diabetes mellitus (GDM) is a heterogeneous disorder that is defined as carbohydrate intolerance with onset or first recognition during pregnancy. Impaired beta-cell function and insulin resistance are the hallmarks of GDM. READ MORE

4. 2. Semi-mechanistic models of glucose homeostasis and disease progression in type 2 diabetes

   Author : Steve Choy; Maria Kjellsson; Mats Karlsson; Willem de Winter; Andrea Mari; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pharmacokinetics; pharmacodynamics; pharmacometrics; glucose homeostasis; insulin; type 2 diabetes; obesity; weight; visceral adipose tissue; HbA1c; non-linear mixed effects; modelling; disease progression; ZDSD rats; Farmaceutisk vetenskap; Pharmaceutical Science;

   Abstract : Type 2 diabetes mellitus (T2DM) is a metabolic disorder characterized by consistently high blood glucose, resulting from a combination of insulin resistance and reduced capacity of β-cells to secret insulin. While the exact causes of T2DM is yet unknown, obesity is known to be a major risk factor as well as co-morbidity for T2DM. READ MORE

5. 3. Protein Profiling and Type 2 Diabetes

   Author : Tea Sundsten; Peter Bergsten; Leif Jansson; Maria Sörhede Winzell; Uppsala universitet; []
   Keywords : Cell biology; Type 2 diabetes; Protein profiling; SELDI-TOF MS; Proteomics; Cellbiologi;

   Abstract : Type 2 diabetes mellitus (T2DM) is a heterogeneous disease affecting millions of people worldwide. Both genetic and environmental factors contribute to the pathogenesis. The disease is characterized by alterations in many genes and their products. READ MORE

6. 4. Candidate Genes for Late Diabetic Complications

   Author : Eero Lindholm; diabetes och endokrinologi Genomik; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TNF; sekretion; LTA; Endocrinology; nephropathy; diabetes mellitus; retinopathy; neuropathy; genetic; UCP; diabetologi; AGER; MHc2TA; HLA-DQB1; Endokrinologi; secreting systems; diabetology;

   Abstract : Diabetes mellitus is a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both. The new WHO criteria for classification of diabetes takes into account also clinical stages dividing the diabetic patients into noninsulin requiring (NIR), insulin requiring for control (IRC) and insulin requiring for survival (IRS) subgroups. READ MORE

7. 5. Chronic exertional compartment syndrome of the lower leg : a novel diagnosis in diabetes mellitus: a clinical and morphological study of diabetic and non-diabetic patients

   Author : David Edmundsson; Göran Toolanen; Per Stål; Jorma Styf; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Chronic compartment syndrome; diabetes mellitus; Orthopaedics; Ortopedi; Orthopaedics; ortopedi;

   Abstract : Chronic exertional compartment syndrome (CECS) of the lower leg, defined as a condition with exercise-induced pain due to increased intramuscular pressure (IMP), has previously mainly been described in running athletes, and etiologic factors are poorly described. CECS has not been reported to occur together with other diseases and information about consequences on muscles morphology after treatment with fasciotomy is largely unknown. READ MORE