Search for dissertations about: "thesis in tuberculosis antigen"

Showing result 1 - 5 of 31 swedish dissertations containing the words thesis in tuberculosis antigen.

2. 1. Immunological aspects of latent tuberculosis infection during pregnancy

   Author : Fregenet Tesfaye Tegegn; Klinisk infektionsmedicin; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Interferon-γ; immune mediators; latent tuberculosis infection; Mtb-antigen reactivity; pregnancy; QuantiFERON-TB Gold Plus;

   Abstract : Pregnancy-induced immune modulation might lead to reactivation of latent tuberculosis infection (LTBI). This thesis explores aspects of immune-based LTBI diagnostics and how pregnancy affects the immune control of Mycobacterium tuberculosis (Mtb) infection. We studied a prospective cohort of women recruited during pregnancy in Ethiopia. READ MORE

4. 2. Mucosal immunity in the respiratory tract : The role of IgA in protection against intracellular pathogens

   Author : Ariane Rodríguez; Carmen Fernández; Lennart Hammarström; Stockholms universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mucosal immunity; respiratory tract; IgA; intracellular pathogens; Immunology; Immunologi;

   Abstract : The lungs and upper airways are mucosal surfaces that are common site for infection with an enormous variety of inhaled pathogens. Therefore, induction of immune responses in the respiratory tract is crucial for protection against respiratory diseases. One of the pathogens infecting the host via the respiratory tract is Mycobacterium Tuberculosis. READ MORE

5. 3. Does IgA play a role in protection against pulmonary tuberculosis?

   Author : Anna Tjärnlund; Carmen Fernandez; Antonio Barragan; Stockholms universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; Immunologi;

   Abstract : More than a century after the identification of the tubercle bacillus and the first attempts at vaccination, tuberculosis (TB) still remains one of the world’s most serious infectious diseases. TB is typically a disease of the lung, which serves both as port of entry and as the major site of disease manifestation. READ MORE

6. 4. Helminths and immunity against tuberculosis

   Author : Daniel Elias; Karolinska Institutet; Karolinska Institutet; []
   Keywords : tuberculosis; BCG; helminths; immunomodulation; vaccination;

   Abstract : The efficacy of Bacille Calmette Guerin (BCG) is low and incidence of tuberculosis (TB) is high in those areas where helminths are endemic. Protection against tuberculosis requires strong cell mediated immunity while chronic helminth infections induce responses characterized by dominant Th2 responses as well as up-regulated regulatory T cell activity. READ MORE

7. 5. Studies on new tuberculosis vaccine candidates in animal models

   Author : Melles Haile; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Background: Tuberculosis (TB) is a major health problem in many countries, especially in low income countries. Globally, TB causes more than 2 million human deaths annually and 1/5 of all adult deaths in developing countries. WHO estimates that one third of the world's population i.e. READ MORE