Search for dissertations about: "thesis in tuberculosis"

Showing result 1 - 5 of 186 swedish dissertations containing the words thesis in tuberculosis.

  1. 1. Dynamics of tuberculosis infection in Sweden

    University dissertation from Lund University

    Author : Niclas Winqvist; Lund University.; Lunds universitet.; [2011]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Tuberculosis; latent tuberculosis infection; long-term follow-up; Øresund region; interferon-gamma release assay; tuberculin skin test;

    Abstract : Sweden provides a special setting for epidemiological and demographic studies of tuberculosis (TB) infection over time for principally two reasons; first, the Swedish TB epidemic has undergone a tremendous transition since the end of the 19th century, when TB was highly endemic, to the current situation with practically interrupted indigenous transmission since several decades. Second, an increasing proportion of persons who grew up before TB transmission virtually disappeared in the 1960s are reaching advanced age, and thus creating conditions that predispose to reactivation of latent TB infection (LTBI). READ MORE

  2. 2. Epidemiological aspects of tuberculosis in Guinea-Bissau, West Africa

    University dissertation from Per Gustafson, Department of Infectious Diseases, University Hospital MAS, SE-205 02 Malmö, Sweden

    Author : Per Gustafson; Lund University.; Lunds universitet.; [2003]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; tuberculin skin test; Infections; Infektioner; survival; mortality; case fatality rate; risk factor; incidence; Guinea-Bissau; Africa; epidemiology; Mycobacterium tuberculosis; HIV-2; HIV-1; HIV; Tbc; Tuberculosis; TB;

    Abstract : Tuberculosis (TB) has plagued the humanity for several thousands of years. The bacteria causing TB is mainly spread from person to person as an aerosol transmission. It is estimated that one third of the world’s population is infected with the disease; about 10% of these will develop active TB during their lifetime. READ MORE

  3. 3. The Role of Zinc in Leishmaniasis and Tuberculosis

    University dissertation from Lund University

    Author : Miguel Guzman; Lund University.; Lunds universitet.; [2014]
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Cutaneous leishmaniasis; tuberculosis; zinc supplementation; lymphocytes; cell proliferation; INF-γ; CD4 CD8 ratio;

    Abstract : The synergistic relation between nutritional deficiency and infection may have negative effects on the immune system, making individuals more vulnerable to infection. Zinc can affect the resistance to infections by modulating cytokine release, and by acting as a cofactor of thymulin, which induces the differentiation of immature T lymphocytes. READ MORE

  4. 4. Interplay of human macrophages and Mycobacterium tuberculosis phenotypes

    University dissertation from Linköping University Electronic Press

    Author : Johanna Raffetseder; Linköpings universitet.; Linköpings universitet.; [2016]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mycobacterium tuberculosis; tuberculosis; macrophage; innate immunity; host-pathogen interaction; antibiotic tolerance; phagosomal maturation; bacterial phenotype; dormancy; persistence; virulence factor; ESAT-6; ESX-1;

    Abstract : Mycobacterium tuberculosis (Mtb) is the pathogen causing tuberculosis (TB), a disease most often affecting the lung. 1.5 million people die annually due to TB, mainly in low-income countries. READ MORE

  5. 5. Fighting Tuberculosis – Structural Studies of Three Mycobacterial Proteins

    University dissertation from Uppsala : Universitetsbiblioteket

    Author : Alina Castell; Uppsala universitet.; [2008]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Mycobacterium tuberculosis; Rv0216; Rv0130; Mycobacterium smegmatis; branched chain aminotransferase; X-ray crystallography; fatty acid metabolism; NATURAL SCIENCES Chemistry Biochemistry Structural biology; NATURVETENSKAP Kemi Biokemi Strukturbiologi;

    Abstract : This thesis presents the cloning, purification, crystallization, and structural studies of two unknown proteins from Mycobacterium tuberculosis, and of an aminotransferase from Mycobacterium smegmatis. Structural knowledge of these proteins is of highest interest for structure-based drug design, which is one of the approaches that can be used in order to fight tuberculosis (TB). READ MORE