Search for dissertations about: "thesis of infection in Diabetes"

Showing result 1 - 5 of 94 swedish dissertations containing the words thesis of infection in Diabetes.

  1. 1. Markers of Infection in Childhood Autoimmune Diabetes and Related Disorders

    Author : Anna-Lena Nilsson; Celiaki och diabetes; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Autoimmune type 1 diabetes Ljungan virus antibodies Islet autoantibodies HLA;

    Abstract : The main aim of this thesis was to contribute to the knowledge about mechanisms involved in the development of type 1 diabetes (T1D) and other autoimmune diseases in children. Immune markers in relation to genetic propensity in children with autoimmune disease, mainly T1D and a small group of juvenile idiopathic arthritis (JIA) and thyroiditis (THYR), as well as healthy controls have been studied. READ MORE

  2. 2. Effects of Enterovirus Infection on Innate Immunity and Beta Cell Function in Human Islets of Langerhans

    Author : Oskar Skog; Gun Frisk; Olle Korsgren; Åke Lernmark; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 1 diabetes; Enterovirus; Coxsackievirus; Innate immunity; Pancreatic islets; Islet function; Medicinsk vetenskap; Medical Science;

    Abstract : This thesis focuses on enteroviral effects on human pancreatic islets. Most knowledge of viral effects on host cells relies on studies of immortalized cell lines or animal models. The islets represent a fundamentally different and less well studied cellular host. Also, enterovirus has been implicated in the etiology of type 1 diabetes (T1D). READ MORE

  3. 3. Perinatal determinants of type 1 diabetes - A social epidemiological perspective

    Author : Kristian Lynch; Celiaki och diabetes; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; area variance; multilevel modeling; contextual determinants; islet autoantibodies; type 1 diabetes; propensity score matching;

    Abstract : Background and Aims: While the development of type 1 diabetes (T1D) in childhood is in part genetically conditioned, non-genetic/environmental factors seem to play a decisive role in its aetiology. The incidence of T1D has been increasing rapidly during the last years, and its prevalence is higher in countries of high economical welfare like Sweden. READ MORE

  4. 4. The Role of Chlamydia pneumoniae-induced Platelet Activation in Cardiovascular Disease : In vitro and In vivo studies

    Author : Hanna Kälvegren; Torbjörn Bengtsson; Arina Richter; Erik Kihlström; Kenneth Persson; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Chlamydia pneumoniae; Platelet; atherosclerosis; Infection; LDL-oxidation; Percutaneous coronary intervention; Cardiovascular disease; Serotonin; Reactive oxygen species production; Pharmacology; Farmakologi;

    Abstract : The common risk factors for atherosclerosis, such as obesity, high cholesterol levels, sedentary lifestyle, diabetes and high alcohol intake, only explain approximately 50% of cardiovascular disease events. It is thereby important to identify new mechanisms that can stimulate the process of atherosclerosis. READ MORE

  5. 5. Enterovirus Infections of β-Cells : A Mechanism of Induction of Type 1 Diabetes?

    Author : Anna-Karin Berg; Gun Frisk; Torsten Tuvemo; Arne Andersson; Merja Roivainen; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pediatrics; enterovirus; type 1 diabetes; β-cells; human pancreatic islets; picornavirus; chemokines; nitric oxide; Pediatrik; Paediatric medicine; Pediatrisk medicin;

    Abstract : The process of β-cell destruction that leads to type 1 diabetes (T1D) is incompletely understood and it is believed to be a result of both genetic and environmental factors. Enterovirus (EV) infections of the β-cells have been proposed to be involved, however, the effects of EV infections on human β-cells have been little investigated. READ MORE