Search for dissertations about: "thesis on Apoe gene polymorphism"

Showing result 1 - 5 of 17 swedish dissertations containing the words thesis on Apoe gene polymorphism.

2. 1. Coffee and gene interaction. The effect on methionine and lipid metabolism

   Author : Elisabeth Strandhagen; Göteborgs universitet; []
   Keywords : coffee; homocysteine; cholesterol; folate; pyridoxine; MTHFR; APOE; gene; polymorphism; interaction;

   Abstract : Background: Different dietary factors influence the risk of coronary heart disease (CHD), most likely in an interaction with genetic polymorphisms. The knowledge about such interactions is insufficient. Some observational studies have shown an association between coffee and CHD, others have not. Coffee consumption affects some CHD risk factors, e. READ MORE

4. 2. Genes, lifestyle and coronary heart disease risk-epidemiological interaction studies

   Author : Jaana Gustavsson; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Coronary heart disease; gene-lifestyle interaction; APOE; FTO; GHRL; smoking; physical activity; diet; obesity;

   Abstract : Coronary heart disease (CHD) has multifactorial background involving both genetic and lifestyle factors, but much is still unknown about their interactions. The aim of this thesis was to study interactions focusing on apolipoprotein E (APOE), fat mass and obesity-related (FTO) and ghrelin/obestatin prepropeptide (GHRL) genes, as well as smoking, physical activity and diet. READ MORE

5. 3. Genes to remember : imaging genetics of hippocampus-based memory functions

   Author : Karolina Kauppi; Lars Nyberg; Jonas Persson; Guillén Fernández; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Imaging genetics; fMRI; Episodic memory; SNP; KIBRA; BDNF; APOE; Hippocampus; Parahippocampus;

   Abstract : In the field of imaging genetics, brain function and structure are used as intermediate phenotypes between genes and cognition/diseases to validate and extend findings from behavioral genetics. In this thesis, three of the strongest candidate genes for episodic memory, KIBRA, BDNF, and APOE, were examined in relation to memory performance and hippocampal/parahippocampal fMRI blood-oxygen level-dependent (BOLD) signal. READ MORE

6. 4. Olfactory Function : The Influence of Demographic, Cognitive, and Genetic Factors

   Author : Margareta Hedner; Maria Larsson; Lars-Göran Nilsson; Claire Murphy; Stockholms universitet; []
   Keywords : SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Olfaction; odor identification; odor threshold; odor discrimination; aging; gender; ApoE; BDNF; val66met; association study; population-based; Psychology; psykologi;

   Abstract : Olfactory function is affected by demographic, cognitive, and genetic factors. In the present thesis, three empirical studies investigated individual differences in olfactory ability. Study I explored demographic and cognitive correlates in common olfactory tasks; odor detection, odor discrimination, and odor identification. READ MORE

7. 5. Genes predisposing to type 2 diabetes and cardiovascular mortality

   Author : Jenny Fredriksson; diabetes och endokrinologi Genomik; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; APOE; APM1; PPARG; PPARGC1A; survival abalysis; Medicin människa och djur ; Medicine human and vertebrates ; Type 2 Diabetes; cardiovascular mortality; glycogen synthase; adiponectin; GYS1;

   Abstract : Cardiovascular complications are frequent in type 2 diabetes (T2D) and cardiovascular death is the most common cause of death for these individuals. A region on chromosome 19 (19q13) has been indicated by several genome scans as a susceptibility locus for T2D or components of the metabolic syndrome (MetS). READ MORE