Search for dissertations about: "thesis on ESBL"

Showing result 16 - 20 of 31 swedish dissertations containing the words thesis on ESBL.

  2. 16. Antibiotic resistance in Gram-negative bacilli : with focus on cephalosporin resistance mechanisms in Escherichia coli and Klebsiella pneumoniae

    Author : Owe Källman; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Objectives: The objectives of this thesis were to study mechanisms conferring cefuroxime resistance in clinical non-ESBL (extended-spectrum beta-lactamase) producing isolates of Escherichia coli and Klebsiella pneumoniae, as well as the presence of co-resistance to other antibiotics in the K. pneumoniae isolates. READ MORE

  4. 17. Every bug counts : neonatal colonization and infection of Gram-negative bacilli : aspects on antibiotic resistance in Sweden and Ecuador

    Author : Viveka Nordberg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Neonatal infections caused by extended-spectrum beta-lactamase (ESBL)-producing Gramnegative bacilli are associated with high morbidity and mortality. In order to perform targeted preventive interventions against the impacts of antibiotic resistance in neonates, it is crucial to study colonization, infection and the spread of EPE-bacteria. READ MORE

  5. 18. Long-term molecular epidemiology of extended-spectrum β-lactamase producing Escherichia coli in a low-endemic setting

    Author : Anna Fagerström; Bo Söderquist; Paula Mölling; Martin Sundqvist; Katarina Persson; Linus Sandegren; Örebro universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Escherichia coli; extended-spectrum β-lactamase; whole genome sequencing; plasmids; hybrid assembly; environment; IncI1; ST131;

    Abstract : Escherichia coli is a commensal inhabitant in the gastro-intestinal tract of humans and animals but it is also the most common bacterial species causing urinary tract infection, which ranges in severity from distal cystitis to urosepsis and septic shock. During the past decades, the prevalence of antibiotic resistant E. READ MORE

  6. 19. Interactions between innate immune effectors and multidrug resistant bacteria

    Author : Harpa Káradóttir; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Antibiotic resistance is an increasingly difficult problem in the clinic, where conventional antibiotics are failing, and new alternative solutions are in high demand. Infections caused by Gram-negative bacteria with multi drug resistance (MDR) mechanisms are increasing globally, and treatment options are limited. READ MORE

  7. 20. Mechanisms and Dynamics of Carbapenem Resistance in Escherichia coli

    Author : Marlen Adler; Linus Sandegren; Josep Casadesús; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; carbapenem; antibiotic resistance; fitness cost; ESBLs; penicillin-binding proteins; gene amplification;

    Abstract : The emergence of extended spectrum β-lactamase (ESBL) producing Enterobacteriaceae worldwide has led to an increased use of carbapenems and may drive the development of carbapenem resistance. Existing mechanisms are mainly due to acquired carbapenemases or the combination of ESBL-production and reduced outer membrane permeability. READ MORE