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Showing result 1 - 5 of 15 swedish dissertations matching the above criteria.

  2. 1. Inflammation and prostate carcinogenesis : influence of immune characteristics and early-adulthood exposure to inflammatory conditions on prostate cancer risk

    Author : Henrik Ugge; Katja Fall; Sabina Davidsson; Jessica Carlsson; Ove Andrén; Lars Henningsohn; Örebro universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; inflammation; Cutibacterium acnes; acne; appendicitis; cytokines; circulating; inflammation marker; IL6; CXCL8;

    Abstract : Chronic inflammation has been implicated in the development of several types of cancer, and evidence from observational and animal studies suggests that it may play a role also in prostate carcinogenesis. Recent observations have brought Cutibacterium acnes (C. acnes) forward as a possible causative agent in pro-oncogenic prostatic inflammation. READ MORE

  4. 2. Photdynamic therapy for treatment of Acne Vulgaris in clinical studies; dose response and mode of action

    Author : Camilla Hörfelt; Göteborgs universitet; []
    Keywords : Photodynamic therapy; Acne Vulgaris; Delta-aminolaevulinic acid; Methyl-aminolaevulinic acid; Porphyrins; Propionibacterium acnes; Fluorescence imaging;

    Abstract : This thesis deals with the use of photodynamic therapy (PDT) for treatment of Acne Vulgaris. Acne Vulgaris is one of the most common skin disorders. Conventional treatments target the pathogenic factors and include a variety of topical and oral medications such as antibiotics. READ MORE

  5. 3. Characterisation of antibiotic-resistant Propionibacterium acnes from acne vulgaris and other diseases

    Author : Cristina Oprica; Karolinska Institutet; Karolinska Institutet; []
    Keywords : P. acnes; acne vulgaris; clinical isolates; antimicrobial resistance; PFGE.;

    Abstract : Propionibacterium acnes (P. acnes) is an anaerobic, Gram-positive bacterium that belongs to the normal microflora. The skin is the major habitat but it can also be found in other body regions. P. READ MORE

  6. 4. Functional and structural studies on CYP21 mutants in congenital adrenal hyperplasia

    Author : Tiina Robins; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Congenital adrenal hyperplasia; CAH; CYP21; enzyme activity; modeling; genotype phenotype relationships; structure function relationships.;

    Abstract : Congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency is one of the most common autosomal recessive disorders, affecting around 1/10 000 newborns worldwide. A defect in the gene encoding steroid 21-hydroxylase, CYP21, results in impaired synthesis of cortisol and in most cases also aldosterone. READ MORE

  7. 5. Propionibacterium acnes and its phages

    Author : Rolf Lood; Infektionsmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Propionibacterium acnes; biofilm; bacteriophage; Siphovirus; pseudolysogeny; heme oxygenase; free radicals; recombinant protein expression; vector;

    Abstract : Microorganisms are everywhere! They can tolerate many diverse extreme environments, such as the human body. Even though many of us might associate the word microorganism with infections and disease, most are actually either harmless or even beneficial for us. READ MORE