Search for dissertations about: "thesis on bacteriophage therapy"

Found 5 swedish dissertations containing the words thesis on bacteriophage therapy.

2. 1. Site-specific recombination of P2-like phages; possible tools for safe gene therapy : A focus on phage ΦD145

   Author : Sridhar Mandali; Elisabeth Haggård-Ljungquist; Richard Calendar; Stockholms universitet; []
   Keywords : bacteriophage; integrase; site-specific recombination; NATURAL SCIENCES; NATURVETENSKAP; molekylärgenetik; Molecular Genetics;

   Abstract : P2-like bacteriophages integrate their genome into the E. coli host cell by a site-specific recombination event upon lysogenization. The integrative recombination occurs between a specific sequence in the phage genome, attP, and a specific sequence in the host genome, attB, generating the host-phage junctions attL and attR. READ MORE

4. 2. Bacterial viruses targeting multi-resistant Klebsiella pneumoniae and Escherichia coli

   Author : Harald Eriksson; Anders Nilsson; Elisabeth Haggård-Ljungquist; Klas Flärdh; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Bacterial viruses; Bacteriophage; Phage; Phage therapy; multi-resistant bacteria; Klebsiella pneumoniae; molekylärgenetik; Molecular Genetics;

   Abstract : The global increase in antibiotic resistance levels in bacteria is a growing concern to our society and highlights the need for alternative strategies to combat bacterial infections. Bacterial viruses (phages) are the natural predators of bacteria and are as diverse as their hosts, but our understanding of them is limited. READ MORE

5. 3. Infection kinetics, phylogenetics, and host interactions of bacteriophages

   Author : Shazeeda Koonjan; Anders S. Nilsson; Lone Brøndsted; Stockholms universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; bacteriophage biology; infection kinetics; phylogenetics; host interactions; phage therapy; phage ecology and evolution; molekylär biovetenskap; Molecular Bioscience;

   Abstract : Bacteriophages, or as they are most commonly referred to as phages, are viruses which are capable of infecting bacteria. They are environmentally plenty, found everywhere from the ground we walk on to contributing to our microbiome. They are highly diverse, coming in various sizes, shapes, and genomic compositions. READ MORE

6. 4. Protein–DNA Recognition : In Vitro Evolution and Characterization of DNA-Binding Proteins

   Author : Mikael Nilsson; Mikael Widersten; Dan Tawfik; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; In vitro evolution; Phage display; mRNA display; Cro; DNA recognition; repressor; Biokemi; Biochemistry; Biokemi;

   Abstract : DNA-recognizing proteins are involved in a multitude of important life-processes. Therefore, it is of great interest to understand the underlying mechanisms that set the rules for sequence specific protein–DNA interactions. Previous attempts aiming to resolve these interactions have been focused on naturally occurring systems. READ MORE

7. 5. Lactobacilli expressing antibody fragments against pathogens

   Author : Anna Hultberg; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Adherence to mucosal surfaces has been shown to be of great importance in the pathogenesis of various infections in the gastro-intestinal tract. Live recombinant bacteria can be used to deliver active or passive immunity at the mucosal surface, which is the site of entry for the majority of the pathogens. READ MORE