Search for dissertations about: "thesis on biocatalysis"

Showing result 1 - 5 of 72 swedish dissertations containing the words thesis on biocatalysis.

  2. 1. Transaminase Biocatalysis: Applications and Fundamental Studies

    Author : Federica Ruggieri; Per Berglund; Mariarita Bertoldi; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; biocatalysis; enzymatic cascade; transaminase; amine; racemization; PLP; enzyme engineering; Chromobacterium violaceum; protein stability; enzyme stability; molecular dynamics; structural biology; enzyme technology; chiral amines; kinetic resolution; Bioteknologi; Biotechnology;

    Abstract : Biocatalysis is the branch of science at the intersection between chemistry and biology and specifcally dedicated to the application of natural evolvable catalysts, i.e. enzymes, in human-designed chemical processes. Among the array of promising biocatalysts, transaminases (EC 2. READ MORE

  4. 2. On Catalytic Mechanisms for Rational Enzyme Design Strategies

    Author : Charlotte Kürten; Per-Olof Syrén; Rudolf Allemann; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; catalytic mechanisms; terpene cyclase; triterpene cyclase; solvent dynamics; protein hydration; thermodynamics; quantum tunneling; polycyclization; natural compounds; ? ?-hydrolase; esterase; amidase; enzyme engineering; biocatalysis; Bioteknologi; Biotechnology;

    Abstract : Enzymes enable life by promoting chemical reactions that govern the metabolism of all living organisms. As green catalysts, they have been extensively used in industry. However, to reach their full potential, engineering is often required, which can benefit from a detailed understanding of the underlying reaction mechanism. READ MORE

  5. 3. Tools in biocatalysis : enzyme immobilisation on silica and synthesis of enantiopure amines

    Author : Karim Engelmark Cassimjee; Per Berglund; Torkel Berglund; Torbjörn Gräslund; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : This thesis presents two techniques in the field of biocatalysis: An enzyme immobilisation method based on the His6-tag for attachment on modified silica oxide beads, and it’s employment in aqueous and organic medium for synthesis applications. The method functions as a one step extraction and immobilisation protocol. READ MORE

  6. 4. Rational engineering of esterases for improved amidase specificity in amide synthesis and hydrolysis

    Author : Peter Hendil-Forssell; Mats Martinelle; Romas J. Kazlauskas; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Amidase; Biocatalysis; Enzyme; Esterase; Enzyme engineering; Lipase; Substrate specificity; Bioteknologi; Biotechnology;

    Abstract : Biocatalysis is an ever evolving field that uses enzymes or microorganisms for chemical synthesis. By utilizing enzymes that generally have evolved for specific reactions under mild conditions and temperatures, biocatalysis can be a more environmentally friendly option compared to traditional chemistry. READ MORE

  7. 5. Immobilization of feruloyl esterases in mesoporous silica

    Author : Christian Thörn; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Mesoporous materials; Feruloyl esterases; Protein modeling; Biocatalysis; QCM-D; Hydroxycinnamic acids; Enzyme immobilization; Silica;

    Abstract : Feruloyl esterases are a class of enzymes that can be used as biocatalysts for the modification of bioactive hydroxycinnamic acids. In industry, enzyme immobilization is often necessary to stabilize the enzymes and to allow their reuse. READ MORE