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Showing result 1 - 5 of 157 swedish dissertations matching the above criteria.

  2. 1. Cancer risk and predisposition in families with childhood cancer

    Author : Karl-Johan Stjernfelt; Lund Pediatrik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cancer; Pediatric; Childhood Cancer; Heredity; Genetics; predisposition; Familial cancer;

    Abstract : BACKGROUND: Recent whole genome sequencing studies report that up to 6% of the childhood cancer population harbour a pathogenic variant. Identification of families with hereditary cancer may improve early detection of cancer as well as treatment outcome. READ MORE

  4. 2. Genetic factors in childhood cancer. Associations between tumors in childhood and adulthood, and prevalence of germline TP53 mutations

    Author : Susanne Magnusson; Bröstcancer-genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Childhood cancer; hereditary factors; breast cancer; survival; hereditary breast and ovarian cancer; hereditary non-polyposis colorectal cancer; familial malignant melanoma; BRCA1; BRCA2; mismatch repair; CDKN2A; familial risk; multiple childhood tumors; Li-Fraumeni syndrome; TP53; adrenocortical carcinoma; choroid plexus tumors; rhabdomyosarcoma;

    Abstract : The etiology of childhood cancer is largely unknown. Approximately 1-10% of all childhood tumors are associated with known cancer predisposition syndromes. However, the contribution may be underestimated due to the failure to detect patients with genetic susceptibility for cancer when relying on known family pattern and anomalies. READ MORE

  5. 3. Epidemiological aspects on malignant diseases in childhood

    Author : Ann Charlotte Dreifaldt; Lennart Hardell; Ulf Flodin; Örebro universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; childhood cancer; incidence rates; persistent organic pollutants; breast-feeding; MEDICINE; MEDICIN; Oncology; Onkologi; Medicin; Medicine; Onkologi; Oncology;

    Abstract : The trends of malignant diseases in children aged 0 to 14 years, reported to the Swedish Cancer Registry 1960–1998 (n=9 298) were analyzed. The most common diagnoses were leukemia, 29.7%, tumors of the central nervous system (CNS), 27.6%, and lymphomas, 10. READ MORE

  6. 4. Life after childhood cancer

    Author : Eva Berg Doukkali; Karolinska Institutet; Karolinska Institutet; []
    Keywords : childhood cancer;

    Abstract : Young people who have undergone treatment for childhood cancer have a high risk of developing chronic health problems that could have a potential strong impact on their lives. How a childhood cancer experience affects the lives of young survivors has only been studied to a limited extent. READ MORE

  7. 5. Childhood cancer and school

    Author : Margareta af Sandeberg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : childhood cancer;

    Abstract : The school situation is one area identified as being affected during and after treatment for childhood cancer and only studied to a limited extent. A contributing factor to that school absence is not always recommended is uncertainty about whether it increases the risk of infection. READ MORE