Search for dissertations about: "thesis on childhood cancer"

Showing result 21 - 25 of 157 swedish dissertations containing the words thesis on childhood cancer.

  2. 21. LIVING WITH CHILDHOOD CANCER - Family Members’ Experiences and Needs

    Author : Maria Björk; Institutionen för hälsovetenskaper; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Parents; Siblings; Nursing; Child; Family; Childhood Cancer;

    Abstract : The overall aim of this thesis was to elucidate family members’ lived experiences and needs during a child’s cancer trajectory and to describe how the illness and its treatment influence both individuals within the family and the family as a whole. Seventeen families with a child under the age of 13 and newly diagnosed with cancer were followed during the child’s treatment trajectory by means of interviews and observations. READ MORE

  4. 22. Microenvironmental Impact on Tumour Cell Phenotype and Genotype in Adult and Paediatric Tumours

    Author : Hiroaki Yasui; Avdelningen för klinisk genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancer genotype; cancer phenotype; malignant rhabdoid tumour; neuroblastoma; ovarian cancer; tumour evolution; Wilms tumour;

    Abstract : This thesis explores how the tumour microenvironment affects the phenotype and shapes the evolution of cancer cells. It encompasses four separate studies:First, we explored the effect of chemokines on the peritotumoral microenvironment of ovarian cancer. READ MORE

  5. 23. Treatment failure in pediatric acute myeloid leukemia: factors associated with frequency and outcome of resistant disease and relapse

    Author : Lene Karlsson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Acute myeloid leukemia; Relapse; Resistant disease; Measurable residual disease;

    Abstract : Although the prognosis for childhood acute myeloid leukemia (AML) has improved over the last decades to a survival of over 70%, still 30-40 % relapse and 5-10% experience resistant disease with poor prognosis. The aim of this thesis was to perform a detailed analysis of disease characteristics and treatment in children with relapsed and resistant AML to provide means to improve prognosis. READ MORE

  6. 24. Hypoxia-induced phenotypic modulation of human neuroblastoma cells

    Author : Linda Holmquist Mengelbier; Institutionen för translationell medicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicin människa och djur ; Medicine human and vertebrates ; reoxygenation; HIF-2a; HIF-1a; differentiation; hypoxia; neuroblastoma;

    Abstract : Neuroblastoma is a childhood tumour derived from cells of the sympathetic nervous system, which are arrested at low differentiation stages. Low differentiation stage and high tumour stage correlate to poor outcome. READ MORE

  7. 25. Genomic instability and genetic heterogeneity in neuroblastoma tumours

    Author : Niloufar Javanmardi; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neuroblastoma tumour; subclone; mutation; relapse; deep sequencing; tumour supressor gene;

    Abstract : Neuroblastoma (NB), a tumour of the sympathetic nervous system and the most common malignant disease of early childhood, is responsible for 9% of paediatric cancer related deaths. Aggressive NB still constitutes a major clinical problem with survival rates of about 35%. READ MORE