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Showing result 1 - 5 of 110 swedish dissertations matching the above criteria.
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1. Susceptibility to chronic liver disease
Abstract : The onset and the progression of chronic liver disease involve environmental and genetic factors. Hepatic stellate cells (HSCs) are important players in these processes and are the main storage site for retinol. READ MORE
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2. Studies on alcoholic liver disease
Abstract : The overall aim of this thesis was to explore the impact of alcoholic cirrhosis in Sweden, and the relation between drinking patterns and beverage types and alcoholic cirrhosis, and to evaluate the possible role of autoantibodies in the pathogenesis of alcohol related liver disease. We found that rats had appearance of IgG against rat CYP3A 1 and CYP2E 1 during chronic ethanol feeding We found that patients had reactivity against CYP3A4 and CYP2E I in about 20 to 30% and 10 to 20% of the alcoholic sera. READ MORE
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3. Non-Alcoholic Fatty Liver Disease : Aspects on Diagnosis and Long-term Prognosis
Abstract : Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease affecting approximately 25% of the global population and is commonly recognized as the hepatic manifestation of the metabolic syndrome. The histological spectrum of NAFLD ranges from isolated steatosis to non-alcoholic steatohepatitis (NASH), with risk of developing fibrosis and subsequent cirrhosis and hepatocellular carcinoma. READ MORE
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4. Serologic Markers in Screening for Coeliac Disease, Clinical significance and immunogenetic basis
Abstract : The prevalence of coeliac disease (CD) was initially estimated to 1/1537. Based on serial analysis [GA and endomysial antibodies (EMA)], the prevalence was 6/1970 (0.30%). In autoimmune chronic hepatitis 5. READ MORE
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5. Liver-related complications and metabolic comorbidities during long-term follow-up of patients with Non-Alcoholic Fatty Liver Disease
Abstract : Background: Non-alcoholic fatty liver disease (NAFLD) is highly associated with the metabolic syndrome, and due to increasing prevalence of for example obesity it is now the most common liver disease in the world. A minority progress to advanced fibrosis/cirrhosis, which is associated with increased mortality, but it is not entirely clear which patients who have an increased risk of fibrosis. READ MORE