Search for dissertations about: "thesis on cystatin c for gfr"

Showing result 1 - 5 of 10 swedish dissertations containing the words thesis on cystatin c for gfr.

2. 1. Biomarkers of Renal Function in Acute Coronary Syndromes

   Author : Axel Åkerblom; Stefan James; Lars Wallentin; Torbjörn Omland; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cystatin C; glomerular filtration rate; GFR; creatinine; acute coronary syndrome; ACS; kidney; renal; mortality; death; myocardial infarction; Cardiology; Kardiologi; Medicin; Medicine; Internal Medicine; Internmedicin;

   Abstract : The thesis aimed to investigate cystatin C and creatinine-based estimates of glomerular filtration rate (eGFR), both at admission and during follow-up, on the combined endpoint of cardiovascular death and myocardial infarction in patients with acute coronary syndrome (ACS). We also evaluated two cystatin C assays and assessed genetic determinants of cystatin C concentrations. READ MORE

4. 2. Molecular Mechanisms in Amyloid Disorders. Novel Treatment Options in Hereditary Cystatin C Amyloid Angiopathy

   Author : Gustav Östner; Avdelningen för klinisk kemi och farmakologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cystatin C; amyloid; amyloidosis; oligomers; domain swapping;

   Abstract : The pathophysiological process in Alzheimer’s disease and other amyloid disorders usually involves the transformation of a soluble monomeric protein via potentially toxic oligomers into amyloid fibrils. The structure and properties of the intermediary oligomers have been difficult to study due to their instability and dynamic equilibrium with smaller and larger species. READ MORE

5. 3. Aspects of retransfusion of shed blood in cardiac surgery

   Author : Björn Brondén; Anestesiologi och intensivvård; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CABG; cardiotomy suction; lipid microemboli; porcine study; clinical study; cystatin C; creatinine; iohexol clearance; outcome; retransfusion; transfusion; blood.;

   Abstract : The use of cardiotomy suction during open heart surgery with cardiopulmonary bypass (CPB) has a long tradition and often regarded as mandatory. Recently, studies have described potentially negative effects of cardiotomy suction with activation of the complement system, enhanced inflammatory response, hemolysis and coagulopathy. READ MORE

6. 4. A life-course approach to chronic kidney disease : risks and consequences

   Author : Per-Ola Sundin; Scott Montgomery; Katja Fall; Per Sjöström; Dorothea Nitsch; Örebro universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Chronic kidney disease; pneumonia; grip strength; creatinine; cystatin C; adolescence; life-course epidemiology; risk factor; mortality;

   Abstract : Successful primary prevention of chronic kidney disease (CKD) relies on understanding the pathways leading to established disease, including how they extend over the life-course. Projects in this thesis examine risk factors for CKD and consequences of impaired kidney function from a life-course perspective using routinely collected health-data in Swedish registers and research cohort data from the United Kingdom. READ MORE

7. 5. Health effects of environmental lead exposure in children

   Author : Katarina Osman; Karolinska Institutet; Karolinska Institutet; []
   Keywords : children; environmental exposure; biological monitoring; lead; cadmium; mercury; selenium; zinc; copper; magnesium; glutathione peroxidase; selenoprotein P; serum ferritin; serum cystatin C; GFR; protein HC; hearing; kidney;

   Abstract : Children comprise the most susceptible part of the population with regard to lead exposure. The lowest level of lead exposure considered to cause adverse health effects has fallen with time, as the research techniques have improved. READ MORE