Search for dissertations about: "thesis on drug pellets"

Showing result 1 - 5 of 12 swedish dissertations containing the words thesis on drug pellets.

2. 1. Diffusion Controlled Drug Release from Slurry Formed, Porous, Organic and Clay-derived Pellets

   Author : Erik Jämstorp Berg; Maria Strømme; Håkan Engqvist; Susanne Bredenberg; Pentti Tengvall; Nanoteknologi och funktionella material Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Diffusion; Drug delivery; Antithrombotic drugs; Highly potent opioids; Modeling; Clays; Polymers; Pellets; Beads; Materialvetenskap; Materials Science;

   Abstract : Coronary artery disease and chronic pain are serious health issues that cause severe discomfort and suffering in society today. Antithrombotic agents and highly potent analgesics play a critical role in improving the recovery process for patients being treated for these diseases. READ MORE

4. 2. Ceramic Materials as Drug Delivery Systems

   Author : Amina Vazda; Håkan Engqvist; Santos Hélder; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Drug delivery; ceramics; Abuse deterrent; inhalation; single-crystals;

   Abstract : The aim of this thesis is to evaluate ceramic materials for drug delivery drugs applications. Three delivery routes were investigated; abuse-deterrent oral formulation, inhalation, and novel ceramic crystals with drug entrapped. A geopolymer matrix was developed in order to withstand non-medical abuse such as crushing, snorting, extraction etc. READ MORE

5. 3. Preparation of Tablets from Reservoir Pellets with an Emphasis on the Compression Behaviour and Drug Release

   Author : Åsa Tunón; Göran Alderborn; Michael E. Aulton; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutics; multiple unit tablets; extrusion-spheronisation; barrier-coating; modified drug release; pellet types; compaction; tablet properties; deformation; densification; Galenisk farmaci; Pharmaceutics; Galenisk farmaci; galenisk farmaci; Pharmaceutics;

   Abstract : The preparation of multiple unit tablets was investigated in this thesis with the intention of gaining a deeper understanding of some of the factors that influence the properties of such tablets.Initially, three different types of pellets (drug, soft and disintegrant pellets) were combined as a model to investigate the ability of the mixture to form disintegrating tablets. READ MORE

6. 4. Structure evolution of phase-separated EC/HPC films for controlled drug release

   Author : Pierre Carmona; Chalmers tekniska högskola; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; electron microscopy; coarsening; cellulose; phase separation kinetics; drug delivery; phase separation mechanisms; porous film; biopolymer; controlled drug release; confocal laser scanning microscope; spin-coating.;

   Abstract : Porous phase-separated ethylcellulose/hydroxypropylcellulose (EC/HPC) films are used to control drug transport out of pharmaceutical pellets. The drug transport rate is determined by the structure of the porous films that are formed as the water-soluble HPC leaches out. READ MORE

7. 5. Ethyl Cellulose Membranes used in Modified Release Formulations

   Author : Johan Hjärtstam; Chalmers tekniska högskola; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; osmotic pumping; water permeability; drug release; reflectivity; ethyl cellulose; degree of substitution; mechanical strength;

   Abstract : Ethyl cellulose (EC) is a commonly used polymer in modified drug release formulations. The general aim of the present study was to investigate release mechanisms through non-porous EC membranes with hydroxypropyl methyl cellulose (HPMC) contents ranging from 0 to 30% by weight. READ MORE