Search for dissertations about: "thesis on effect of aspirin"

Showing result 1 - 5 of 32 swedish dissertations containing the words thesis on effect of aspirin.

2. 1. Experimental studies on thrombosis and thrombolysis : With special reference to importance of lys-plasminogen, active site thrombin inhibitors and stable fish oil

   Author : Liying Chen; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; Thrombolysis; thrombosis; recombinant tissue-type plasminogen activator; lys- and glu-plasminogen; aspirin; thrombin inhibitors; platelets; superoxide dismutase; stable fish oil; Kirurgi; Surgery; Kirurgi; rättsmedicin; Forensic Medicine;

   Abstract : Dissolution and prevention of thrombus in the atherosclerotic coronary artery have become an important part of treatment therapy of acute myocardial infarction. However, the currently most effective thrombolytic agent, recombinant tissue-type plasminogen activator (rt-PA), only elicits 80% recanalization of thrombotically occluded coronary arteries and early occlusion occurs in about 40% of successfullyrecanalized vessels. READ MORE

4. 2. The Role of Chlamydophila Pneumoniae in the Inflammatory Response and Expansion of Abdominal Aortic Aneurysms

   Author : Lars Karlsson; Håkan Pärsson; David Bergqvist; Janet Powell; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Abdominal aortic aneurysm; Chlamydophila pneumoniae; inflammation; aspirin; statin; expansion; randomised clinical trial; Vascular surgery; Kärlkirurgi; Surgery; kirurgi;

   Abstract : Abdominal aortic aneurysm (AAA) is a common disease that develops gradually over several years and is characterised by weakening and dilatation of the aortic wall. AAAs also demonstrates a marked inflammatory infiltrate throughout the aortic wall. Chlamydophila pneumoniae (C. pneumoniae), is a common bacterium. READ MORE

5. 3. Angiotensin converting enzyme inhibition and aspirin in congestive heart failure

   Author : Tord Juhlin; Kardiologiska klinikens forskargrupp; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; clinical trial; ARBs; renal function; congestive heart failure; ischaemic heart disease; NSAIDs; ACE-inhibitors; aspirin; dose dependency; Cardiovascular system; Kardiovaskulära systemet;

   Abstract : Angiotensin-converting enzyme (ACE) inhibitors act by decreasing production of angiotensin II and by potentiating the effects of bradykinin by inhibition of its breakdown. Bradykinin exerts part of its effects via vasodilating prostaglandins. Since the cyclooxygenase (COX)-inhibitors, e.g. READ MORE

6. 4. Platelet Inhibition in Coronary Artery Disease – Mechanisms and Clinical Importance : Studies with Focus on P2Y12 Inhibition

   Author : Christoph Varenhorst; Stefan James; Agneta Siegbahn; Lars Wallentin; Steen Dalby Kristensen; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; coronary artery disease; myocardial infarction; acute coronary syndromes; stent thrombosis; P2Y12 inhibitors; thienopyridines; clopidogrel poor response; clopidogrel; prasugrel; Cardiology; Kardiologi; Kardiologi; Cardiology;

   Abstract : Despite the currently recommended dual antiplatelet treatment (DAT) with aspirin and P2Y12 inhibition in patients with coronary artery disease (CAD) there is a risk of adverse clinical outcome. Pharmacodynamic (PD) poor response to clopidogrel occurs in ~ 30% of clopidogrel-treated patients and is associated with an increased risk of recurrent thrombotic events. READ MORE

7. 5. Influence of leukotriene D4 and cyclooxygenase-2 on cell survival

   Author : Katarina Wikström; Malmö Experimentell patologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pathological anatomy; Patologi allmän ; General pathology; colorectal cancer; inflammation; apoptosis; LTD4; COX-2; patologisk anatomi;

   Abstract : The pro-inflammatory effect of leukotrienes is an important element in the pathogenesis of multiple disorders, including asthma and inflammatory bowel diseases (IBD). A serious concern for IBD patients is the increased risk of developing colorectal cancer and since there seems to be a general connection between inflammation and cancer we hypothesised that LTD4 induced signalling events could be involved in increasing the tumourgenic potential of cells. READ MORE