Search for dissertations about: "thesis on experimental pathology"

Showing result 1 - 5 of 73 swedish dissertations containing the words thesis on experimental pathology.

2. 1. Experimental studies on glioma cell motility and proliferation

   Author : Adila Salih El-Obeid; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; glioma; TGF-α; EGFR; GFAP; motility; Genetik; Clinical genetics; Klinisk genetik; Pathology; patologi;

   Abstract : Glioma is a malignant primary brain tumor associated with short patient survival. Various growth factors and cytoskeletal proteins are correlated to glioma progression. In this thesis the effects of transforming growth factor alpha (TGFα) and glial fibrillary acidic protein (GFAP) were studied. READ MORE

4. 2. Oligodendrocyte pathology following Traumatic Brain Injury : Experimental and clinical studies

   Author : Johanna Flygt; Niklas Marklund; Fredrik Piehl; Uppsala universitet; []
   Keywords : Traumatic brain injury; oligodendrocytes; oligodendrocyte progenitor cells; interleukin 1-β; central fluid percussion injury; Neurokirurgi; Neurosurgery; Neurokirurgi; Neurosurgery;

   Abstract : Traumatic brain injury (TBI) caused by traffic and fall accidents, sports-related injuries and violence commonly results in life-changing disabilities. Cognitive impairments following TBI may be due to disruption of axons, stretched by the acceleration/deceleration forces of the initial impact, and their surrounding myelin in neuronal networks. READ MORE

5. 3. Expression of TGF- isoforms, their receptors and related SMAD proteins in brain pathology : Immunohistochemical studies focusing on infarcts, abscesses and malignant gliomas

   Author : Ahmad Khaled Ata; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; TGF-beta receptor; SMAD; brain; infarct; abscess; glioma; experimental; human; Genetik; Clinical genetics; Klinisk genetik; Genetics; genetik;

   Abstract : This thesis focuses on the immunohistochemical expression of transforming growth factor beta(TGFβ) isoforms, their receptors and TGF-β-related SMAD proteins in brain pathology, chiefly in-farcts. One key question was whether the expressions of these compounds are altered within glial cells, endothelial cells of microvessels and other cell types in the vicinity of infarcts. READ MORE

6. 4. Inflammatory mechanisms in experimental CNS trauma

   Author : Jonas Isaksson; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; Spinal cord injury; brain injury; ICAM-1; P-selectin; iNOS; inflammation; Genetik; Clinical genetics; Klinisk genetik; Pathology; patologi;

   Abstract : Traumatic brain and spinal cord injuries are important causes of premature death and permanentdisability. To improve the treatment of CNS-injured patients increased knowledge about thepathophysiological events that mediate death or dysfunction of nervous tissue is urgently needed. READ MORE

7. 5. Healing of endosseous implants with different surface characteristics in grafted and non-grafted bone : clinical and experimental studies

   Author : Måns Jungner; Stefan Lundgren; Malou Hultcrantz; Carina Lundqvist; Peter Nilsson; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Dental implants; surface characteristics; bone graft; maxillary sinus; implant survival; oxidized surface; turned surface; sinus membrane elevation; bone formation; macrophages; osteocalcin; osteopontin; CD68; odontologi; Odontology;

   Abstract : Aims: This study uses radiological and clinical evaluations of the healing of endosseous titanium implants presented with different surface characteristics in the clinical situation (paper I-III) and experimentally to describe the early bone healing in maxillary sinus membrane elevation with and without the use of grafting material (paper IV).Material and methods: In paper I, 136 patients were treated with 394 dental implants – 199 were oxidized titanium implants (Nobel Biocare TiUnite) and 195 were turned titanium surface implants (Nobel Biocare Mark III). READ MORE