Search for dissertations about: "thesis on method development and validation"

Showing result 1 - 5 of 244 swedish dissertations containing the words thesis on method development and validation.

  1. 1. Drug Analysis : Bioanalytical Method Development and Validation

    Author : Mikaela Malm; Yngve Bergqvist; Anders Colmsjö; Uppsala universitet; []
    Keywords : Analytical chemistry; African trypanosomiasis; calibration model; chiral chromatography; dried blood spots; eflornithine; evaporative light-scattering detection; HIV AIDS; lamivudine; liquid chromatography; malaria; nevirapine; piperaquine; pneumonia; solid-phase extraction; sulfadoxine; sulfamethoxazole; validation; zidovudine; Analytisk kemi;

    Abstract : This thesis describes bioanalytical methods for drug determination in biological matrixes, with drugs in focus used against diseases largely affecting low-income countries. Solid-phase extraction is used for sample cleanup, and processed samples are analyzed by liquid chromatography. READ MORE

  2. 2. Simulation of welding and heat treatment : modelling and validation

    Author : Henrik Alberg; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Datorstödd maskinkonstruktion; Computer Aided Design;

    Abstract : Many aerospace components with complex geometry are fabricated from smaller parts using joining techniques such as welding. Welding and the heat treatment which usually follows, can result in unwanted deformation and stresses. READ MORE

  3. 3. Qualitative and Quantitative Assessment of Integration Testing for Model-Based Software in the Automotive Industry

    Author : Jan Schröder; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; Industrial Case Studies; Software Quality; Validation; Software Metrics; Maintainability; Software Engineering; Empirical Research; Technical Debt;

    Abstract : Background: Integration testing of vehicle software in the automotive industry relies heavily on simulation models. As they replicate actual vehicle functions in the testing process, they increase in size and amount of interconnectivity as rapidly as the actual functions. Valid simulation models are a precondition for valid integration testing. READ MORE

  4. 4. On the Realization of Credible Simulations in Aircraft Development : Efficient and Independent Validation Enabled by Automation

    Author : Robert Hällqvist; Petter Krus; Magnus Eek; Robert Braun; Gerhard Schmitz; Linköpings universitet; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Aircraft Vehicle Systems; Credibility Assessment; FMI; Interoperability; Modelica; Modeling and Simulation; Model integration; SSP;

    Abstract : Designing modern aircraft is not an easy task. Today, it is not enough to optimize aircraft subsystems at a subsystem level. Instead, a holistic approach is necessary whereby the constituent subsystems need to be designed for the best joint performance. READ MORE

  5. 5. Prediction of Energy Use of a Swedish Secondary School Building : Building Energy Simulation, Validation, Occupancy Behaviour and Potential Energy-Efficiency Measures

    Author : Jessika Steen Englund; Bahram Moshfegh; Mathias Cehlin; Jan Akander; Tomas Persson; Högskolan i Gävle; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; building energy simulation; school building; field measurements; energy use; heat power demand; validation; occupancy behaviour; airing; energy-efficiency measures; byggnadssimulering; skolbyggnad; fältmätningar; energianvändning; värmeeffektbehov; validering; brukarbeteende; vädring; energieffektiviseringsåtgärder; Hållbar stadsutveckling; Sustainable Urban Development;

    Abstract : Residential and public buildings account for about 40% of the annual energy use in Europe. Many buildings are in urgent need of renovation, and reductions in energy demand in the built environment are of high importance in both Europe and Sweden. Building energy simulation (BES) tools are often used to predict building performance. READ MORE