Search for dissertations about: "thesis on thyroid carcinoma"

Showing result 1 - 5 of 28 swedish dissertations containing the words thesis on thyroid carcinoma.

  2. 1. Regulatory Effects of TGF-β Superfamily Members on Normal and Neoplastic Thyroid Epithelial Cells

    Author : Åsa Franzén; Paschalis Sideras; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; activin; BMP; cadherin; carcinoma; cell cycle arrest; dedifferentiation; EGF; growth inhibition; invasion; Smad; TGF-β; thyroid; Genetik; Clinical genetics; Klinisk genetik; Pathology; patologi;

    Abstract : Thyroid growth and function is partly regulated by growth factors binding to receptors on the cell surface. In the present thesis, the transforming growth factor-β (TGF-β) superfamily members have been studied for their role in regulation of growth and differentiation of both normal and neoplastic thyroid epithelial cells. READ MORE

  4. 2. Growth factor receptor signalling in thyrocytes of normal and neoplastic origin

    Author : Daniel Bergström; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; thyroid; carcinoma; HGF; Met; TGF-β; EGF; receptor signalling; Genetik; Clinical genetics; Klinisk genetik; Pathology; patologi;

    Abstract : Cellular growth and function are controlled by stimulatory and inhibitory factors actingthrough specific receptors. The present thesis focuses on the role of growth factors, theirreceptors and signalling pathways in normal and neoplastic thyroid epithelial cell biology. READ MORE

  5. 3. Interactions between the stroma and thyroid epithelial cells of normal and malignant origin

    Author : Thérèse Dahlman; Uppsala universitet; []
    Keywords : Medical sciences; Thyroid gland; carcinoma; collagen type I; EGF; TGF-b1; interaction; integrins; E-cadherin; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicine; medicin;

    Abstract : Endocrine and locally produced factors as well as interactions between epithelial cells and the stroma important in the control of growth and function of the thyroid gland. In this study, the effects of, and mechanism(s) for, such cross-talk under some normal and pathological conditions were investigated. READ MORE

  6. 4. Tumor Stroma in Anaplastic Thyroid Carcinoma : Interstitial Collagen and Tumor Interstitial Fluid Pressure

    Author : Ellen Lammerts; Lucio Nitsch; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; Collagen I synthesis; Fibrosis; Tumor - stroma interactions; PDGF; TGF-β; Inhibitor; Cell cycle; Tumor growth; Hyaluronan; Biokemi; Biochemistry; Biokemi; Medical Biochemistry; medicinsk biokemi;

    Abstract : Anaplastic thyroid carcinoma (ATC) is an aggressive malignancy in man with stromal fibrosis as one of the main features. Carcinoma cells synthesized no or little collagen I protein. READ MORE

  7. 5. Molecular aspects of post-Chornobyl and sporadic papillary thyroid carcinoma

    Author : Andrii Dinets; Karolinska Institutet; Karolinska Institutet; []
    Keywords : papillary thyroid carcinoma;

    Abstract : Papillary thyroid carcinoma (PTC) exhibits various molecular abnormalities, both when sporadic and radiation-related. PTC is still diagnosed in adult individuals who were younger than 18 years at the time of the Chornobyl accident in 1986 and lived within the contaminated area. READ MORE