Search for dissertations about: "thiazoline fused 2-pyridones"

Found 2 swedish dissertations containing the words thiazoline fused 2-pyridones.

  1. 1. Synthesis of substituted Ring-Fused 2-Pyridones and applications in chemical biology

    Author : Christoffer Bengtsson; Fredrik Almqvist; Paul Helquist; Umeå universitet; []
    Keywords : Synthesis; 2-pyridone; 2-thiazoline; cross coupling; pili; curli; antibacterial; organisk kemi; Organic Chemistry;

    Abstract : Antibiotics have been extensively used to treat bacterial infections since Alexander Fleming’s discovery of penicillin 1928. Disease causing microbes that have become resistant to antibiotic drug therapy are an increasing public health problem. READ MORE

  2. 2. Synthesis of Ring-fused Peptidomimetics : Interacting with Amyloid Fibrils

    Author : Dan E. Adolfsson; Fredrik Almqvist; Anna Linusson; Morten Grötli; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; organic chemistry; synthesis; peptidomimetics; thiazoline fused 2-pyridones; Alzheimer s disease; Parkinson s disease; Amyloid; Amyloid-beta; alfa-Synuclein; method development; organisk kemi; Organic Chemistry;

    Abstract : Parkinson's and Alzheimer's disease are the two most common neurological disorders in humans. Both conditions involve progressive death of neurons in the central nervous system, decline in bodily functions and eventually (and invariably), death. So far, no cure exists and the available treatments can only ease symptoms. READ MORE