Search for dissertations about: "thioesterase"
Showing result 1 - 5 of 10 swedish dissertations containing the word thioesterase.
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1. Strain- and bioprocess-design strategies to increase production of (R)-3-hydroxybutyrate by Escherichia coli
Abstract : Microbial bio-based processes have emerged as an alternative to replace fossil-based processes for the production of fuels and chemicals. (R)-3-hydroxybutyrate (3HB) is a medium-value chemical that has gained special attention as a precursor of antibiotics and vitamins, as a monomer for the synthesis of tailor-made polyesters and as a nutritional source for eukaryotic cells. READ MORE
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2. Molecular cloning and characterization of the murine acyl-CoA thioesterase CTE-I
Abstract : Mouse cytosolic type I acyl-CoA thioesterase (CTE-I) is a member of the type I family of acylCoA thioesterases. These enzymes hydrolyze acyl-CoAs to non-esterified fatty acids (NEFAs) and Coenzyme A (CoA-SH) and are strongly induced in rodent liver by a diverse group of compounds called peroxisome proliferators. READ MORE
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3. The type-I acyl-CoA thioesterase/acyltransferase gene family : linking structure to function
Abstract : Acyl-CoA thioesterases hydrolyse acyl-CoAs to non-esterified fatty acids and coenzyme A (CoASH), thereby regulating intracellular levels of these compounds. We have recently identified and initiated characterisation of a novel, unique gene family of acyl-CoA thioesterases/acyltransferases, called the Type-I acyl-CoA thioesterase/acyltransferase gene family. READ MORE
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4. Characterization of peroxisome proliferator-activated receptor alpha (PPARa) regulated acyl-CoA thioesterases involved in lipid metabolism
Abstract : The peroxisome proliferator-activated receptor alpha (PPARalpha) is a key nuclear receptor in the control of lipid metabolism. Target genes for PPARalpha include many enzymes involved in the oxidation of fatty acids in mitochondria and peroxisomes. READ MORE
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5. Acyl-CoA thioesterases : auxiliary enzymes in peroxisomal lipid metabolism
Abstract : Peroxisomes are small organelles essential for life, which carry out a variety of functions mostly related to lipid metabolism, including α- and β-oxidation as well as the first steps of plasmalogen biosynthesis. Peroxisomal β-oxidation metabolizes many different lipids including very long-chain fatty acids, dicarboxylic fatty acids, branched-chain fatty acids, eicosanoids and certain xenobiotic fatty acids. READ MORE