Search for dissertations about: "thioglycoside promoter"

Found 2 swedish dissertations containing the words thioglycoside promoter.

  2. 1. Development of a Novel Promoter System for Thioglycoside Activation; and its application in the synthesis of a GD3 bis-lactam

    Author : Andréas Meijer; Centrum för analys och syntes; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; GD3; Organic chemistry; bis-lactam; ganglioside; thioglycoside; promoter; iodine monobromide; glycosylation; iodine monochloride; Organisk kemi;

    Abstract : A novel promoter system IX/AgOTf (X=Cl or Br) for thioglycoside activation has been developed (paper I-II). The promoter system has been evaluated in the synthesis of two GD3 bis-lactam fragments (paper III)... READ MORE

  4. 2. Some New Methods in Sialic Acid Chemistry

    Author : Teddy Ercegovic; Centrum för analys och syntes; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; thioglycoside promoter; ganglioside; Tumor-associated antigen; lactam; lactone; sialic acid; N-acetylneuraminic acid; Neu5Ac; sialyl donor; auxiliary group; 3- S -phenylthio; bis-sialic acid lactam; 3- S -phenylseleno; silver trifluoromethanesulfonate; iodine monochloride; Organic chemistry; Organisk kemi;

    Abstract : Gangliosides (G) are sialic acid-containing cell surface glycosphingolipids capable of forming lactones, i.e. inner esters. Some gangliosides are tumor-associated antigens, and they may serve as immunogens in their lactone form, where the latter is comparatively more abundant on the surface of malignant cells. READ MORE