Search for dissertations about: "thiophene"

Showing result 6 - 10 of 43 swedish dissertations containing the word thiophene.

  2. 6. Designing thiophene-based fluorescent probes for the study of neurodegenerative protein aggregation diseases : From test tube to in vivo experiments

    Author : Andreas Åslund; Peter Konradsson; Ian Nicholls; Linköpings universitet; []
    Keywords : TECHNOLOGY; TEKNIKVETENSKAP;

    Abstract : Protein aggregation is an event related to numerous neurodegenerative diseases, such as Alzhemier’s disease and prion diseases. However little is known as to how and why the aggregates form and furthermore, the toxic specie may not be the mature fibril but an on route or off route specie towards mature aggregates. READ MORE

  4. 7. Fluorescent thiophene-based ligands for detection and characterization of disease-associated protein aggregates

    Author : Therése Klingstedt; Peter Nilsson; Per Hammarström; Henrik Zetterberg; Linköpings universitet; []
    Keywords : ;

    Abstract : In this thesis the unique optical properties of fluorescent ligands termed luminescent conjugated oligothiophenes (LCOs) have been used to study a variety of protein aggregates associated with human protein misfolding disease. This heterogeneous group of diseases contains well known and fatal members such as Alzheimer´s and Huntington´s disease and the development of sensitive tools for the detection and characterization of protein aggregates is crucial for unravelling the complexity of these pathologies. READ MORE

  5. 8. Synthesis of donor–acceptor–donor thiophene based ligands that can be utilized for optical assignment of pathological targets

    Author : Linda Lantz; Peter Nilsson; Peter Konradsson; Jerker Mårtensson; Linköpings universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : Thiophene based ligands represent a class of molecular reporters proven superior in discerning pathological targets involved in neurodegenerative diseases, as well as bacterial infection. By fluorometric detection that depends on the milieu surrounding the ligand these biological processes can be studied with fluorescence spectroscopy and hyper-spectral confocal microscopy. READ MORE

  6. 9. Structure and properties of poly (3-alkyl thiophenes)

    Author : Marie-Louise Lagerstedt-Eidrup; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; molecular weight; blends; thermal degradation; structure; interactions; miscibility; NMR; poly 3-alkyl thiophene ; chromism; Mark-Houwink; SEC;

    Abstract : .... READ MORE

  7. 10. Structural chemistry and optical application

    Author : Mohamed I D M Ghazzali; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; conjugated polymers; single crystal x-ray diffraction; porphyrins; NLO-materials;

    Abstract : The demand for materials with optical activities against LASER radiation has been extensively increased over the last decade with the development of sophisticated high energetic LASER sources. The goal is to obtain organic or metal-organic molecules capable of increasing their absorptions against LASER irradiance while still maintaining a degree of transmittance. READ MORE