Search for dissertations about: "thrombi"

Showing result 1 - 5 of 14 swedish dissertations containing the word thrombi.

  2. 1. Aspects of Plasminiogen Activator Inhibitor 1 in Metabolic Syndrome

    Author : Karin Mossberg; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PAI-1; metabolic syndrome; obesity; type 2 diabetes; cardiovascular disease; fibrinolysis; thrombi; plasma; platelets; adipose tissue; mRNA; qPCR; reference gene;

    Abstract : Plasminogen activator inhibitor 1 (PAI-1) is the main inhibitor of the fibrinolytic system and binds irreversibly to tissue-type plasminogen activator (t-PA), and thereby inhibits the protective action of t-PA against thrombus formation. Elevated levels of plasma PAI-1 is observed in subjects with type 2 diabetes (T2D) and the metabolic syndrome (MetS), which is a combination of metabolic features including obesity. READ MORE

  4. 2. Left ventricular thrombus and stroke after acute myocardial infarction

    Author : Thomas Mooe; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; myocardial infarction; thrombolytic therapy; left ventricular thrombosis; risk factors; cerebral embolism and thrombosis;

    Abstract : A left ventricular thrombus develops in approximately 40% of patients following an anterior myocardial infarction. Embolization from these thrombi has been regarded as the most important cause of stroke following a myocardial infarction. READ MORE

  5. 3. Pre-Clinical Evaluation of a Novel Radiotracer for the Diagnosis of DVT and Pulmonary Embolism

    Author : David Edwards; Håkan Ahlström; Stuart McCully; Hans Johnsson; Uppsala universitet; []
    Keywords : Radiology; Radiologisk forskning;

    Abstract : Deep vein thrombosis (DVT) and pulmonary embolism (PE) are different aspects of a single condition, venous thrombo-embolic disease (VTE), a major cause of morbidity and mortality in the western world. Rapid diagnosis is critical, as timely medical intervention can have a substantial beneficial effect on the mortality rate. READ MORE

  6. 4. ADAMTS13 phenotype in health and disease with special reference to thrombotic thrombocytopenic purpura

    Author : Minola Manea Hedström; Lund Pediatrik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Urology; tubular cells; podocytes; kidney; plasma; ADAMTS13; thrombotic thrombocytopenic purpura; nephrology; Urologi; nefrologi; Pediatrics; Pediatri;

    Abstract : Von Willebrand factor (VWF) is synthesized and secreted by endothelial cells into the plasma as a series of multimers. VWF induces the formation of platelet plugs at sites of vascular injury and high shear stress. Biological activity is dependent on multimeric size, which is regulated in plasma by the VWF-cleaving protease ADAMTS13. READ MORE

  7. 5. Studies of the role of complement factor H in hemolytic uremic syndrome

    Author : Fariba Vaziri Sani; Lund Pediatrik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pediatri; Pediatrics; Hemolytic uremic syndrome; complement system; factor H;

    Abstract : Factor H is the main fluid phase regulator of the alternative pathway of complement. Factor H acts as a co-factor for factor I-mediated C3b degradation, inhibits the formation of the C3bBb convertase and accelerates its decay. By discriminating between host and foreign cells, factor H inhibits complement-mediated injury to host cells. READ MORE