Search for dissertations about: "thrombosis in cancer"

Showing result 1 - 5 of 30 swedish dissertations containing the words thrombosis in cancer.

  2. 1. Platelets – Multifaceted players in tumor progression and vascular function

    Author : Yanyu Zhang; Anna-Karin Olsson; Gertraud Orend; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cancer; Tumor; Platelet; HRG; PDGFB; TBK1; NETs; Angiogenesis; EMT; Metastasis; Medicinsk vetenskap; Medical Science; Oncology; Onkologi; Biologi med inriktning mot molekylär cellbiologi; Biology with specialization in Molecular Cell Biology;

    Abstract : Platelets play a crucial role for blood hemostasis, the process that prevents bleeding. In addition, platelets have been demonstrated to promote cancer progression and cancer related complications like metastasis and thrombosis. READ MORE

  4. 2. Endothelial and cardiac effects of 5-fluorouracil. An experimental and clinical study

    Author : Sara Kinhult; Bröstcancer-genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancerology; oncology; Cytology; endothelin; onkologi; Cytologi; cancer; von Willebrand factor; thrombomodulin; lipoperoxidation; probucol; low-molecular weight heparin; scanning electron microscopy; 5-fluorouracil; endothelium;

    Abstract : The cytostatic drug 5-fluorouracil (5-FU) has been shown to affect both morphology and function of vascular endothelium. These effects could be part of the pathophysiology for 5-FU induced cardiotoxicity. The present thesis explores the mechanisms of this endothelial toxicity. READ MORE

  5. 3. Neutrophil extracellular traps in cancer and cancer-associated thrombosis

    Author : Axel Rosell; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Cancer is associated with a hypercoagulable state, and venous thromboembolism (VTE) may be the first sign of occult cancer. Cancer screening of all patients presenting with VTE would, however, overload the healthcare system and burden patients with unnecessary investigations. READ MORE

  6. 4. Neutrophil extracellular traps as potential therapeutic targets to prevent tumor-induced organ failure and metastasis

    Author : Melanie Herre; Anna-Karin Olsson; Jessica Cedervall; Peetra Magnusson; Benoit Ho-Tin-Noé; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neutrophil extracellular traps; NETs; cancer; metastasis; inflammation; organ dysfunction; thrombosis; Oncology; Onkologi;

    Abstract : Cancer does not only affect surrounding tissues, but also leads to complications at distant sites. The reason for this is that tumors secrete factors and prime cells that travel through the body, making cancer a systemic disease. In fact, cancer death is mostly caused by systemic complications such as metastasis, organ failure or thrombosis. READ MORE

  7. 5. Rare complications in cancer surgery

    Author : Johan Björklund; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Background: Curative cancer surgery aims to reduce mortality and morbidity related symptoms caused by the cancer. The surgery is often done at a time when the patient is presenting lesser or no symptoms and at a time when the cancer is not presenting an immediate threat to the patient’s life. READ MORE