Search for dissertations about: "thrombosis"

Showing result 11 - 15 of 201 swedish dissertations containing the word thrombosis.

  2. 11. On the regulation and effects of chronic inflammation in inflammatory bowel disease

    Author : Olof Grip; Gastroenterologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Gastroenterologi; statins; monocytes; eosinophils; dysplasia; thrombosis; ulcerative colitis; Crohn s disease; inflammation; inflammatory bowel disease; Gastro-enterology;

    Abstract : Inflammatory bowel disease is thought to result from the inappropriate and ongoing activation of the mucosal immune system driven by the presence of normal luminal flora. In this process monocytes/macrophages contribute to and maintain chronic inflammation by being both regulatory and effector cells. READ MORE

  4. 12. Aspects on Imaging and Endovascular Treatment of Aortic Dissection and Aneurysm

    Author : Mats-Ola Eriksson; Rickard Nyman; Anders Wanhainen; Johnny Steuer; Mårten Falkenberg; Uppsala universitet; []
    Keywords : Aneurysms; aorta; stents; ultrasound; colour Doppler; vascular; interventional; aortic dissection; complicated; TEVAR; EVAR; re-intervention; survival; thrombosis; false lumen; aortic remodelling; Radiology; Radiologi;

    Abstract : Aortic aneurysm and dissections are potentially life threatening conditions. The advent of endovascular aortic repair (EVAR) and thoracic endovascular aortic repair (TEVAR) has reduced perioperative mortality and morbidity and are now established therapy methods for treatment of aortic disease. READ MORE

  5. 13. The Synthesis and Use of Certain Pyridine Derivatives as Modulators of the G-protein Coupled Receptors mGlu5 and P2Y12

    Author : Peter Bach; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; mGluR5; P2Y12; gastroesophageal reflux disease GERD ; thrombosis; ethyl nicotinates; ureas; sulfonylureas; oxazoles; bioisosteres; regioselectivity; solvent effect.;

    Abstract : The glutamatergic mGlu5 receptor and the purinergic P2Y12 receptor are two important targets in the development of novel treatments of gastroesophageal reflux disease (GERD) and thrombosis, respectively. Synthesis was developed to investigate the structure-activity relationships (SAR) of a novel series of 2-alkynylpyridine derivatives as mGluR5 antagonists. READ MORE

  6. 14. Platelet Adhesion to Proteins in Microplates : Applications in Experimental and Clinical Research

    Author : Andreas Eriksson; Per Whiss; Håkan Wallén; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; platelets; platelet adhesion; platelet assay; synergistic activation; thrombosis; anti-platelet treatment; Pharmacology; Farmakologi;

    Abstract : Platelets are crucial for prevention of blood loss after vessel injury. Platelet adhesion to disrupted vessel walls is mediated by receptors such as the GPIb-IX-V complex that binds von Willebrand factor and the collagen-binding integrin α2β1. READ MORE

  7. 15. Structural and functional studies of factor V in health and disease

    Author : Mårten Steen; Malmö Klinisk kemi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Klinisk kemi; Clinical chemistry; APC resistance and hemophilia; thrombosis; factor VIII; coagulation; factor V;

    Abstract : The homologous blood coagulation factors V (FV) and factor VIII (FVIII) are important at sites of vascular injury for the amplification of the clotting cascade. Activated FV (FVa) serves as a cofactor to the enzyme activated factor X (FXa) in the activation of prothrombin. This complex is called the prothrombinase complex. READ MORE