Search for dissertations about: "thrombotic states"

Found 3 swedish dissertations containing the words thrombotic states.

  2. 1. Thrombin activatable fibrinolysis inhibitor (TAFI) in different hemorrhagic and thrombotic conditions

    Author : Jovan P Antovic; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Thrombin activatable fibrinolysis inhibitor TAFI ; coagulation; fibrinolysis; thrombin; plasmin; factor V Leiden; hemophilia; von Willebrand disease; diabetes mellitus; preeclampsia;

    Abstract : Until recently the coagulation and fibrinolytic systems were usually considered as separate entities. Accounts of a fibrinolysis inhibitor that is generated by thrombin shed more light on this field and changed the concept by giving thrombin, the pivotal enzyme in hemostasis, another important role in the down-regulation of fibrinolysis. READ MORE

  4. 2. Structural pathology and functional analysis of vitamin K-dependent protein S

    Author : Tusar K Giri; Malmö Klinisk kemi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; C4b-binding protein; Protein S; blood coagulation; thrombosis; natural mutations; in vitro characterization.; Immunology; transplantation; serologi; Immunologi; serology;

    Abstract : Protein S deficiency is an autosomal dominant trait affecting around 10% of families thrombophilic families. The high affinity interaction of approximately 60% of protein S with C4b -binding protein (C4BP) has raised a complicated situation for the diagnosis of deficiency states. READ MORE

  5. 3. Coagulation in liver failure : the role of thromboelastometry and fibrinogen

    Author : Gabriel Dumitrescu; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Liver failure is undeniably accompanied by distortions of the coagulation system. The modern theory of coagulation in patients with compensated liver disease (acute or chronic) states that the coagulation system is in a rebalanced state, also displaying prothrombotic tendencies particularly towards the end stages. READ MORE