Search for dissertations about: "thrombotic thrombocytopenic purpura"

Found 4 swedish dissertations containing the words thrombotic thrombocytopenic purpura.

2. 1. Studies of the pathogenesis of hemolytic uremic syndrome and thrombotic thrombocytopenic purpura

   Author : Diana Karpman; Lund Pediatrik; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pediatri; Pediatrics; tumor necrosis factor; interleukin 6; von Willebrand factor; apoptosis; lipopolysaccharide; shiga-like toxin; Escherichia coli O157:H7; Hemolytic uremic syndrome; thrombotic thrombocytopenic purpura; Urology; nephrology; Urologi; nefrologi;

   Abstract : This study investigated the pathogenesis of hemolytic uremic syndrome (HUS) and thrombotic thrombocytopenic purpura (TTP). (1) The relative roles of lipopolysaccharide and Shiga-like toxin-2 were studied in a mouse model of Escherichia coli O157:H7 infection. READ MORE

4. 2. ADAMTS13 phenotype in health and disease with special reference to thrombotic thrombocytopenic purpura

   Author : Minola Manea Hedström; Lund Pediatrik; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Urology; tubular cells; podocytes; kidney; plasma; ADAMTS13; thrombotic thrombocytopenic purpura; nephrology; Urologi; nefrologi; Pediatrics; Pediatri;

   Abstract : Von Willebrand factor (VWF) is synthesized and secreted by endothelial cells into the plasma as a series of multimers. VWF induces the formation of platelet plugs at sites of vascular injury and high shear stress. Biological activity is dependent on multimeric size, which is regulated in plasma by the VWF-cleaving protease ADAMTS13. READ MORE

5. 3. Studies of ADAMTS13 expression and activity in the kidney

   Author : Ramesh Tati; Lund Pediatrik; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ADAMTS13; von WIllebrand factor; thrombotic thrombocytopenic purpura;

   Abstract : Von Willebrand factor (VWF) is an abundant plasma glycoprotein involved in platelet adhesion and aggregation at sites of vascular injury. ADAMTS13 is the sole physiological VWF-cleaving protease, thus regulating the size of thrombus growth. READ MORE

6. 4. Verotoxinogenic Escherichia coli O157:H7 in Swedish cattle and pigs

   Author : Erik Eriksson; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Abstract : Verotoxinogenic E. coli O157:H7 (VTEC O157:H7) can cause severe disease in humans, with bloody diarrhea and complications such as haemolytic uraemic syndrome (HUS), thrombotic thrombocytopenic purpura (TTP) and even death. Animals carry VTEC O157:H7 asymptomatically. READ MORE