Search for dissertations about: "thymectomy"

Found 4 swedish dissertations containing the word thymectomy.

  2. 1. Thymic studies. Investigations into the effects of childhood thymectomy, and characterization of thymic B cells and Hassall's corpuscles

    Author : Christina Lundqvist; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; thymus; thymectomy; TCR; B cells; APC; Hassall s corpuscles; AIRE;

    Abstract : This thesis focuses on the human thymus, a primary lymphoid organ responsible for the maturation of T cells. Progenitors arrive from the bone marrow and start to randomly assemble their T cell receptor (TCR) followed by a thorough selection process in which the TCR is tested for functionality and autoreactivity. READ MORE

  4. 2. Early childhood thymectomy - impact on immune function

    Author : Judith Gudmundsdottir; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Immunologi; Thymus; Pediatric cardiac surgery; Congenital heart defect;

    Abstract : Introduction: The thymus is the site of T cell maturation. Children born with a congenital heart defect often endure surgery early in life, and during surgery their thymus is routinely removed, as it blocks the surgeons access to the heart. READ MORE

  5. 3. New Biomarkers for Neuromuscular Function and Myasthenia Gravis

    Author : Carl Johan Molin; Anna Rostedt Punga; Johan Widenfalk; Nils Hailer; Jan Verschuuren; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biomarkers; myasthenia gravis; neuromuscular function; neurophysiology;

    Abstract : Myasthenia gravis (MG) is an autoimmune disorder, which is caused by autoantibodies against the acetylcholine receptor (AChR). The cardinal symptom is muscle fatigue, which can range from slight weakness of the extraocular muscles (causing droopy eyelids or double vision), to paralysis of the respiratory muscles. READ MORE

  6. 4. Myasthenia gravis : clinical aspects and possible involvement of prolactin

    Author : Natalia Tsinzerling; Karolinska Institutet; Karolinska Institutet; []
    Keywords : myasthenia gravis; prolactin; immune regulation; thymic pathology; thymoma; immunosuppressive treatment;

    Abstract : Myasthenia gravis (MG) is an autoimmune disease characterized by the production of antibodies against the skeletal muscle acetylcholine receptor (AChR). MG is usually associated with thymic disorders including thymoma (about 10%) and lymphofollicular hyperplasia (HPL) (up to 80%). READ MORE