Search for dissertations about: "thymine analogue"
Found 3 swedish dissertations containing the words thymine analogue.
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1. DNA and RNA base analogue FRET - from fluorophore design to biochemical applications
Abstract : This thesis focuses on the development and use of fluorescent base analogues (FBAs). They are important tools in research concerning nucleic acids structure, dynamics and interactions. READ MORE
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2. Expanding the alphabet of fluorescent nucleic acid base analogues: Characterization of new members
Abstract : Fluorescence has proven to be a powerful tool for studying structure, dynamics and interactions of biomolecules such as proteins, RNA and DNA. However, since the natural DNA/RNA nucleobases are virtually non-fluorescent, there is a need for developing fluorescent nucleic acid markers. READ MORE
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3. A biophysical study of nucleic acid interactions with analogues and drugs
Abstract : work presented in this thesis concerns studies on the physicochemical nature of interactions between nucleic acids and small ligands. The outcome of such studies can yield insights at a molecular level into the physiological mechanisms of action of biologically active nucleic-acid binding molecules. READ MORE