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Showing result 1 - 5 of 271 swedish dissertations matching the above criteria.

  2. 1. Thyroid cancer : studies on etiology and prognosis

    Author : Arne Hallquist; Lennart Hardell; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Thyroid cancer; prognostic factors; etiology; occupation; medical ionizing radiation; reproductive; and family factors;

    Abstract : Thyroid cancer constitutes about 1% of all malignant tumours and the incidence is increasing in Sweden. It is rare in children before the age of 10. During puberty the female to male ratio increases to be two to three times more common in females. The ratio remains constant until menopause and thereafter declines. READ MORE

  4. 2. DNA damage affecting thyroidal iodide transport: an explanation to thyroid stunning

    Author : Madeleine Nordén; Göteborgs universitet; []
    Keywords : thyroid; radioiodide; thyroid stunning; NIS; cell cycle; genotoxic stress; DNA damage; H2AX; ATM;

    Abstract : 131I is widely used clinically in the treatment of Graves´ disease and differentiated thyroid cancer. However, cellular and molecular effects of 131I irradiation in relation to absorbed dose are poorly documented. READ MORE

  5. 3. Molecular regulation of thyroid development. New mechanisms of normal and defective morphogenesis

    Author : Henrik Fagman; Göteborgs universitet; []
    Keywords : thyroid; congenital hypothyroidism; thyroid dysgenesis; cadherins; pharyngeal arch arteries; Shh; Tbx1;

    Abstract : Congenital hypothyroidism (CH) is untreated a major cause of mental retardation. The majority of cases are due to malformations of the gland (dysgenesis). Little is known of molecular mechanisms regulating thyroid morphogenesis. READ MORE

  6. 4. Calcium Homeostasis After Thyroid Surgery

    Author : Pia Lindblom; Lund Kirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PTH-peripheral effects; hPTH- 1-34 infusion; EDTA infusion; Set-point; Vitamin D3; PTH; Calcium; Thyroid surgery; Postoperative hypocalcemia; Bone density.; Surgery; orthopaedics; traumatology; Kirurgi; ortopedi; traumatologi; Reduced thyroid hormones;

    Abstract : Calcium homeostasis after thyroid surgery was studied during the immediate postoperative period and after one year. One day after hemithyroidectomy ionised calcium decreased whereas basal PTH did not change. EDTA stimulated maximal and total PTH secretion and set-point decreased on postoperative day 1 and normalised on day 7. READ MORE

  7. 5. Affective disorders and their treatments : implications for thyroid function

    Author : Ingrid Lieber; Ursula Werneke; Michael Ott; Mats Eliasson; John McGrath; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Bipolar disorder; affective disorder; lithium; thyroid dysfunction; hyperthyroidism; hypothyroidism; Delphi-consensus; psykiatri; Psychiatry;

    Abstract : BackgroundThe relationship between affective disorders, mood-stabilisers and thyroid dysfunction is complex and poorly understood. Symptoms of thyroid dysfunction can overlap with symptoms of affective disorder, destabilise mood, and impact physical health. READ MORE