Search for dissertations about: "time in therapeutic range TTR"

Found 5 swedish dissertations containing the words time in therapeutic range TTR.

2. 1. Warfarin treatment quality in stroke prevention

   Author : Fredrik Björck; Anders Själander; Peter Svensson; Per Wester; Christine Kremer; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anticoagulation; atrial fibrillation; complications; international normalized ratio INR variability; persistence; stroke; time in therapeutic range TTR ; treatment quality; warfarin; cardiovascular disease; hjärt- och kärlforskning;

   Abstract : BackgroundIschemic stroke is a serious condition often associated to presence of atrial fibrillation (AF). Use of anticoagulants for AF patients greatly reduces the risk of stroke. Warfarin is the most commonly used anticoagulant in Sweden. The aim of this thesis was to study the impact of warfarin treatment quality in Swedish stroke prevention. READ MORE

4. 2. Anticoagulation treatment in patients with a mechanical heart valve

   Author : Bartosz Grzymala-Lubanski; Anders Själander; Peter J. Svensson; David Bergqvist; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mechanical heart valve; anticoagulation; warfarin; Time in Therapeutic Range TTR ; INR variability;

   Abstract : BackgroundEvery year about 2,500 patients in Sweden undergo surgery for heart valve disease, primarily in the aortic valve.  In contrast to the mitral valve, which can be repaired in 70% of the cases, the aortic valve is normally replaced by a mechanical or biological prosthesis. READ MORE

5. 3. Anticoagulants in kidney disease

   Author : Frida Welander; Anders Själander; Henrik Holmberg; Emöke Dimény; Marie Evans; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anticoagulants; atrial fibrillation; chronic kidney disease; dialysis; DOAC; ischemic stroke; major bleeding; nephrotic syndrome; venous thromboembolism; warfarin.; Medicine; medicin;

   Abstract : Background: Patients with chronic kidney disease (CKD) and atrial fibrillation (AF) are at high risk of ischemic stroke. Evidence is lacking if patients with advanced CKD or on dialysis benefit from oral anticoagulants (OAC) as stroke prophylaxis. READ MORE

6. 4. Oral anticoagulation treatment in atrial fibrillation - To bleed or not to bleed, that is the question

   Author : Mattias Wieloch; Malmö Institutionen för kliniska vetenskaper; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; anticoagulation; atrial fibrillation; hemorrhage; kidney; warfarin; epidemiology; stroke;

   Abstract : Background: Oral antigoagulation treatment (OAT) with warfarin have a narrow therapeutic window and patients exhibit a highly variable doseresponse that is attributable to genetic, disease-related,and environmental factors as well as prescription and nonprescription drugs, dietary vitamin K and alcohol. The effect of warfarin treatement on blood coagulation is measured using international normalized ratio (INR). READ MORE

7. 5. Oral anticoagulation and stroke risk

   Author : Vilhelm Sjögren; Anders Själander; Per Wester; Peter J Svensson; Mia von Euler; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Stroke; warfarin; atrial fibrillation; dabigatran; rivaroxaban; apixaban; low-molecular-weight heparin; bridging;

   Abstract : Background: The risk of ischaemic stroke in patients with atrial fibrillation (AF) and mechanical heart valve (MHV) prostheses can be reduced by oral anticoagulation (OAC), which increases the risk of serious bleeding. The aims of this thesis were [1] to find out how effective and safe warfarin is where treatment quality is high, i.e. READ MORE