Search for dissertations about: "time-of-flight mass spectrometry"

Showing result 1 - 5 of 90 swedish dissertations containing the words time-of-flight mass spectrometry.

  1. 1. Metabolic Studies with Liquid Separation Coupled to Mass Spectrometry

    Author : Erik Allard; Jonas Berguist; Per Sjöberg; Risto Kostiainen; Uppsala universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; liquid chromatography; mass spectrometry; tandem mass spectrometry; method development; capillary electrophoresis; electrospray ionization; time-of-flight; quantitation; metabolomics; metabonomics; pattern recognition; ximelagatran; melagatran; charge state; Analytical chemistry; Analytisk kemi; Analytical Chemistry; analytisk kemi;

    Abstract : Metabolism is the sum of all chemical processes with the purpose to maintain life, as well as enable reproduction, in a living organism. Through the study of metabolism, increased understanding of pharmacological mechanisms and diseases can be achieved. READ MORE

  2. 2. Precision mass measurements : Final limit of SMILETRAP I and the developments of SMILETRAP II

    Author : Andreas Solders; Reinhold Schuch; Juha Äystö; Stockholms universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; SMILETRAP; Precision mass spectrometry; Penning trap; Atomic mass; Highly charged ions; Low energy ion storage; Time of flight ion cyclotron resonance; High frequency; Proton mass; QED; g-factor; Physics; Fysik; Physics; fysik;

    Abstract : The subject of this thesis is high-precision mass-measurements performed with Penning trap mass spectrometers (PTMS). In particular it describes the SMILETRAP I PTMS and the final results obtained with it, the masses of 40Ca and that of the proton. READ MORE

  3. 3. Atomic laser resonance ionization mass spectrometry

    Author : Lars Bengtsson; Chalmers University of Technology; []
    Keywords : resonacne ioniation spectroscopy; photoionization; resonant photoexcitaiton; time-of-flight mass spectrometer; resonance ionization mass spectrometry; laser ablation; isotope selectivity; RIMS; RIS;

    Abstract : .... READ MORE

  4. 4. Quantitative Bioanalysis : Liquid separations coupled to targeted mass spectrometric measurements of bioactive compounds

    Author : Björn Arvidsson; Jonas Bergquist; Magnus Wetterhall; Gérard Hopfgartner; Uppsala universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; Analytical chemistry; Method development; Enhanced microdialysis; Column switching; Liquid chromatography; Capillary electrophoresis; Electrospray ionization; Mass spectrometry; Triple quadrupole; Time-of-flight; Quantitation; Validation; Analytisk kemi;

    Abstract : Performing quantitative analysis of targeted bioactive compounds in biological samples, such as blood plasma, cerebrospinal fluid or extracts from pig liver, put high demands on the ruggedness of the method acquiring the results. In addition to the complexity of the sample matrix, the bioactive compounds targeted for analysis usually have low levels of natural abundance, further increasing the demand on the analytical method sensitivity. READ MORE

  5. 5. Molecular and epidemiological studies on eyes with pseudoexfoliation syndrome

    Author : Amelie Botling Taube; Jonas Bergquist; Albert Alm; Eva Larsson; Hannu Uusitalo; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pseduoexfoliation syndrome; PEX; aqueous humor; cataract; cataract surgery; lens capsule; proteomics; mass spectrometry; MS; MALDI TOF MS MS; quantitative proteomics; iTRAQ; dimethyl labeling; imaging mass spectrometry; IMS; time of flight secondary ion mass spectrometry; TOF-SIMS; crystallin; epidemiology; risk factor; Ophtalmology; Oftalmiatrik;

    Abstract : Pseudoexfoliation (PEX) syndrome is an age-related condition characterized by the production and accumulation of extracellular fibrillary material in the anterior segment of the eye. PEX predisposes for several pathological conditions, such as glaucoma and complications during and after cataract surgery. READ MORE