Search for dissertations about: "time-of-flight secondary ion mass spectrometry"

Showing result 1 - 5 of 29 swedish dissertations containing the words time-of-flight secondary ion mass spectrometry.

  1. 1. Molecular and epidemiological studies on eyes with pseudoexfoliation syndrome

    Author : Amelie Botling Taube; Jonas Bergquist; Albert Alm; Eva Larsson; Hannu Uusitalo; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pseduoexfoliation syndrome; PEX; aqueous humor; cataract; cataract surgery; lens capsule; proteomics; mass spectrometry; MS; MALDI TOF MS MS; quantitative proteomics; iTRAQ; dimethyl labeling; imaging mass spectrometry; IMS; time of flight secondary ion mass spectrometry; TOF-SIMS; crystallin; epidemiology; risk factor; Ophtalmology; Oftalmiatrik;

    Abstract : Pseudoexfoliation (PEX) syndrome is an age-related condition characterized by the production and accumulation of extracellular fibrillary material in the anterior segment of the eye. PEX predisposes for several pathological conditions, such as glaucoma and complications during and after cataract surgery. READ MORE

  2. 2. Mass spectrometry of biopolymers based on ion-induced desorption

    Author : Roman Alexandrovich Zubarev; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Radiation sciences; Strålningsvetenskap; Radiation biology; Strålningsbiologi; Ion Physics; jonfysik;

    Abstract : Various aspects of biopolymer molecular characterization by their molecular masses havebeen studied, with emphasis on ion-induced desorption and time-of-flight mass Spectrometry(TOF MS). Limitations of the average-isotopic mass concept, as well as the utility ofaccurate monoisotopic mass measurements for deriving amino-acid and elementalcompositions, are discussed. READ MORE

  3. 3. Analysis of phospholipids in cellular membranes with LC and imaging mass spectrometry

    Author : Ingela Lanekoff; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : Mass spectrometry; TOF-SIMS; Phospholipid; Cells; Anammox;

    Abstract : Imaging mass spectrometry enables the creation of molecule specific images from the surface of a solid sample in vacuum. To solve the issue of bringing single cells into vacuum without altering their native distribution of molecules, a freeze fracture device that fits the time of flight secondary ion mass spectrometry (TOF-SIMS) IV instrument has been developed. READ MORE

  4. 4. Imaging mass spectrometry for in situ lipidomics: from cell structures to cardiac tissue

    Author : Sanna Sämfors; Chalmers University of Technology; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Myocardial infarction; PC12 cells; Cell membrane; Mass spectrometry imaging; Sample preparation; Lipidomics; ToF-SIMS; Gas cluster ion beam;

    Abstract : Imaging of cells and tissues is important for studying different processes within biological systems due to the spatial information provided for different molecular species during imaging. One powerful imaging technique is mass spectrometry imaging (MSI). READ MORE

  5. 5. Single fluid inclusion analysis using ToF-SIMS : Implications for ancient Earth biodiversiy and paleoenvironment studies

    Author : Sandra Siljeström; Jukka Lausmaa; Andrew Steele; Stockholms universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; ToF-SIMS; time-of-flight secondary ion mass spectrometry; fluid inclusions; biomarkers; hopanes; steranes; early life; paleoenvironment; oil; eukaryotes; Earth sciences; Geovetenskap; geokemi; Geochemistry;

    Abstract : When and how life first emerged on the Earth is an area of intense research. Signs of the first life on Earth, including morphological fossils, are scarce and hard to interpret. An alternative approach is to study organic biomarkers, which are molecular fossils commonly considered as bona fide biosignatures. READ MORE