Search for dissertations about: "tissue factor pathway inhibitor"

Showing result 1 - 5 of 38 swedish dissertations containing the words tissue factor pathway inhibitor.

  1. 1. Tissue Factor in Complex Studies of interactions between blood coagulation proteins

    University dissertation from Linköping : Linköping University Electronic Press

    Author : Karin Carlsson; Magdalena Svensson; Susanne Wisén; [2010]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURAL SCIENCES; NATURVETENSKAP;

    Abstract : Many biological processes rely on specific protein-protein interactions, for example immune responses, cell signaling, transcription, and blood coagulation. Blood coagulation is initiated when a vessel wall is damaged, exposing tissue factor (TF) to the circulating factor VII/factor VIIa (FVII/FVIIa) which results in the formation of the TF:FVIIa complex and thereby the initiation of blood coagulation. READ MORE

  2. 2. Vitamin K-dependent protein S - studies of synthesis, structure and function

    University dissertation from Clinical Chemistry, Malmö

    Author : Sofia Somajo; Lund University.; Lunds universitet.; [2014]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; C4b-binding protein; coagulation; microparticles; protein C; protein S; structure; tissue factor pathway inhibitor;

    Abstract : This thesis is based on four projects with the overall aim to investigate vitamin K-dependent protein S functions in relation to its structure. The anticoagulant functions of protein S can be divided in three: 1) cofactor for activated protein C (APC), 2) cofactor for tissue factor pathway inhibitor (TFPI) and 3) APC and TFPI-independent anticoagulant functions. READ MORE

  3. 3. Leukemia inhibitor factor (LIF) and gp130 in early defence against HIV-1 infection

    University dissertation from Stockholm : Karolinska Institutet, Department of Medicine at Huddinge University Hospital

    Author : Annelie Tjernlund; Karolinska Institutet.; Karolinska Institutet.; [2006]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; LIF; HIV-1; lymphoid tissue; cytokine; innate immune response; Jak Stat signalling pathway; cMAGI cells; siRNA;

    Abstract : Leukemia inhibitor factor (LIF) is a polyfunctional cytokine that belongs to the IL-6 family which mainly signals through the Jak/Stat pathway via the gp130/LIFR- heterodimer. The focus of my research has been to investigate and understand if and how LIF exerts HIV1 suppressing activity. READ MORE

  4. 4. Growth factor regulation of the urokinase plasminogen activator (uPA) system in human endometrium, and the significance of uPA receptor activation in endometrial angiogenesis

    University dissertation from Institutionen för Obstetrik och gynekologi, Universitetssjukhuset, 22185 Lund

    Author : Tove Sandberg; Lund University.; Lunds universitet.; [2000]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obstetrics; endothelial cell migration; angiogenesis; uPA:PAI-1 complex; uPAR; TGF-beta; PAI-1; EGF; uPA; Growth factor; gynaecology; andrology; reproduction; sexuality; Obstetrik; gynekologi; andrologi; reproduktion; sexualitet;

    Abstract : The purpose of this thesis was to examine the role of growth factors and the urokinase plasminogen activator (uPA) system in human endometrial angiogenesis. Growth factors as well as progesterone increased expression of the main inhibitor of uPA (PAI-1) in primary cultures of endometrial stromal cells. READ MORE

  5. 5. Metabolic and endocrine function of human adipose tissue with focus on regional differences

    University dissertation from Stockholm : Karolinska Institutet, Department of Medicine at Huddinge University Hospital

    Author : Vanessa van Harmelen; Karolinska Institutet.; Karolinska Institutet.; [2001]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; acylation stimulating protein; adipocytes; adipose tissue heterogeneity; adrenoceptors; insulin; leptin; lipogenesis; lipolysis; noradrenaline; plasminogen activator inhibitor-1; preadipocytes; tumour necrosis factor-cc;

    Abstract : The major function of human adipose tissue is to store excess ingested energy and to release free fatty acids after hydrolysis of triglycerides (lipolysis), to meet the energy demands of other organs. Adipose tissue also has a secretory function. READ MORE