Search for dissertations about: "tissue factor pathway inhibitor"

Showing result 11 - 15 of 45 swedish dissertations containing the words tissue factor pathway inhibitor.

2. 11. Genetic association studies in stroke

   Author : Claes Ladenvall; Göteborgs universitet; []
   Keywords : stroke; ischemic stroke subtypes; subarachnoid hemorrhage; genetics; polymorphism; fibrinolysis; tPA; PAI-1; TAFI; CRP; Factor XIII;

   Abstract : Stroke is the third most common cause of death and the most common cause of disability in adults in developed countries. It is a complex disease in which genetic and environmental factors make about equal contributions. READ MORE

4. 12. Expression and regulation of MMP-1 and MMP-3 in human gingival fibroblasts

   Author : Helena Domeij; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Matrix metalloproteinases; tissue inhibitor of metalloproteinases; gingival fibroblasts; monocytes; periodontal diseases;

   Abstract : Matrix metalloproteinases (MMPs) are a group of proteolytic enzymes collectively responsible for the metabolism of extra cellular matrix components. Disturbance of the physiological balance between MMPs and their endogenous inhibitors, tissue inhibitors of metalloproteinases (TIMPs), is implicated in several inflammatory diseases characterized by tissue degradation. READ MORE

5. 13. Human polymorphonuclear granulocytes in inflammation : studies with an emphasis on nitric oxide

   Author : Gerd Lärfars; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Polymorphonuclear granulocytes; inflammation; nitric oxide; leukotrienes; tumor necrois factor; rheumatoid arthritis; interferon-gamma; chronic granulomatous disease;

   Abstract : The function of the polymorphonuclear neutrophil granulocyte (PMN) is of vital importance in inflammation. For the defense against infections PMNs are armored with different weapons such as chemotaxis, phagocytosis and production of cytotoxic substances. READ MORE

6. 14. Haemostatic function in precocious myocardial infarction and vein graft occlusion after coronary artery bypass grafting

   Author : Elisabeth Moor; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : The present study examined the role of blood coagulation and fibrinolytic function in patients with coronary heart disease in two settings; in patients with precocious myocardial infarction in whom thrombosis is considered to constitute an important pathogenic mechanism and in unselected patients undergoing coronary artery bypass grafting (CABG) in whom early thrombotic occlusion of vein grafts is a considerable problem. Particular attention was paid to coagulation factor Vll and the tissue factor pathway inhibitor (TFPI) in the young post-infarction patients. READ MORE

7. 15. The impact of Bcl-3 expression and signaling in cancer

   Author : Karunakar Saamarthy; Avdelningen för translationell cancerforskning; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cyclin D1; BCL3ANT; Colorectal cancer; Melanoma; Prostate cancer; ID; IL-6; Bcl-3;

   Abstract : Bcl-3 is a proto-oncogene and belongs to the inhibitor of κB (IκB) family and is known to be upregulated in numerous cancers. Bcl-3 can initiate transcription of different genes involved in cell survival and cell growth. READ MORE