Search for dissertations about: "tissue sections"

Showing result 21 - 25 of 166 swedish dissertations containing the words tissue sections.

  1. 21. Generation and characterization of antibodies for proteomics research

    Author : Karin Larsson; Sophia Hober; John McCafferty; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; antibody; antibody validation; immunohistochemistry; immunofluorescence; tissue microarray; Western blot; epitope mapping; antigen design; Bioengineering; Bioteknik;

    Abstract : Specific antibodies are invaluable tools for proteomics research. The availability of thoroughly validated antibodies will help to improve our understanding of protein expression, localization and function; fundamental processes and features of all living organisms. READ MORE

  2. 22. Rectal Cancer - Tumor Biology and Prognostic Markers

    Author : Eva Fernebro; Bröstcancer-genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; prognostic markers; Cytology; oncology; cancerology; Cytologi; onkologi; cancer; immunohistochemistry IHC ; chromosomal instability CIN ; microsatellite instability MSI ; tissue microarray TMA ; tissue inhibitor of metalloproteinase 1 TIMP-1 ; Rectal cancer; soluble urokinase plasminogen activator receptor suPAR ;

    Abstract : Colorectal cancer is one of our most common malignancies and the second leading cause of cancer death worldwide. About 1/3 of the tumors are located in the rectum. READ MORE

  3. 23. Visualizing and profiling tissue lipids by ToF-SIMS imaging mass spectrometry

    Author : Dalila Belazi; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Time-of-flight secondary ion mass spectrometry (ToF-SIMS) is an emerging surface analytical method for chemical microanalysis of biological samples. While much work has been done with artificial materials and some with cultured cells and animal tissue, very little ToF-SIMS work has been done so far with clinically relevant tissue samples. READ MORE

  4. 24. Human ovulation. Studies on collagens, gelatinases and tissue inhibitors of metalloproteinases

    Author : Anna Karin Lind; Göteborgs universitet; []
    Keywords : ovulation; ovary; human; follicle; collagen; MMP and TIMP;

    Abstract : Ovulation is a highly regulated process, which involves the degradation and rupture of healthy tissue of the ovarian follicle and the extrusion of a fertilizable oocyte. This unique biological process is initiated by the LH-surge, which induces major vascular changes and remodelling of the extracellular matrix (ECM) in and around the follicle. READ MORE

  5. 25. Combining mass spectrometric tissue imaging with conventional histology : focus on Alzheimer’s disease

    Author : Santiago Solé Domènech; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Historically, most scientific discoveries have been accompanied by previous technological innovation. Representative examples are the introduction of gene sequencing technologies, which allowed for the mapping of the human genome, or the constant improvement in the microscopy field that lead to the introduction of modern multiphoton imaging techniques, allowing for live imaging of body organs in animal specimens. READ MORE