Search for dissertations about: "tissue-resident"
Showing result 1 - 5 of 40 swedish dissertations containing the word tissue-resident.
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1. Lung-resident, M2e-specific CD4 T cells critically protect during influenza infection
Abstract : Memory CD4+ T cells are a critical component of the adaptive immune response to fight infection. However, current vaccines against influenza only focus on the other arm of adaptive immunity—triggering B cells to produce antibodies. READ MORE
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2. Macrophages in Crohn's Disease: lnnate immune cellular and molecular mechanisms driving intestinal inflammation and fibrosis
Abstract : Macrophages and their interactions with the lamina propria and luminal microenvi-ronment are crucial in the pathogenesis of Crohn´s disease (CD), a chronic inflamma-tory disease with a strong inflammatory innate immune involvement. Therefore, in-terpreting macrophage activity in the intestinal microenvironment may identify treatment targets beneficial for at least a subgroup of patients. READ MORE
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3. Studies of the Pancreas: Implications for Type 1 Diabetes Aetiology
Abstract : Type 1 diabetes (T1D) is a disease of severe insulin deficiency through loss of β cells in the endocrine pancreas. The T1D dogma maintains that a precipitating event unleashes autoimmunity in at-risk individuals, often measured through autoantibodies against β cell antigens. READ MORE
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4. Immune cell composition and cytokine expression in the pregnant and non-pregnant uterus
Abstract : The success of implantation and further development of the embryo is heavily dependent on the endometrial immune cell composition and its ability to communicate with fetal semi-allogeneic trophoblast cells. Although our understanding of the immune cell population in the uterus has improved, its precise role in normal reproduction and reproductive disorders is still not fully resolved. READ MORE
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5. The role of liver myeloid cells in obesity and metabolic disease
Abstract : Macrophages are tissue resident cells with diverse phenotypes and functions depending on their origin, localization and physiological context. In the liver, their main functions are to detoxify the blood from pathogens, debris and metabolic waste arriving to the liver through the systemic and portal circulation. READ MORE