Search for dissertations about: "tissue-resident"

Showing result 21 - 25 of 40 swedish dissertations containing the word tissue-resident.

  2. 21. T cells in solid tumors : investigating the immunomodulation in the tumor microenvironment

    Author : Ciputra Adijaya Hartana; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The immune system protects human from cancer through an immunosurveillance mechanism. However, the progressive nature of tumor cells to differentiate and the complexity of the tumor microenvironment may result in the immunomodulation of immune cells. READ MORE

  4. 22. A Study of Eosinophils – From the Human Thymus to Eosinophilic Esophagitis

    Author : Sofie Albinsson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Eosinophil; Eosinophilic esophagitis; Galectin-10; Human; Patient-reported outcome; T cell; Thymocyte; Thymus;

    Abstract : Eosinophils are cells of the innate immune system. They primarily reside within tissues and are most numerous in the gastrointestinal tract but are absent from the healthy esophagus. During the inflammatory disease eosinophilic esophagitis, eosinophils infiltrate the esophagus but their function is unknown. READ MORE

  5. 23. Hematopoiesis: Functional Insights by Cell Fate Conversion

    Author : Martin Wahlestedt; Institutionen för experimentell medicinsk vetenskap; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Blood cell formation, or hematopoiesis, is maintained by rare hematopoietic stem cells (HSCs) residing in the bone marrow (BM). HSCs may self-renew (the process whereby HSCs replicate to produce new HSCs) to preserve their own numbers, as well as initiate a highly coordinated hierarchical differentiation process that results in the production of mature effector blood cells. READ MORE

  6. 24. Resident T cells in human skin : functional heterogeneity and clinical implications

    Author : Stanley Sing Hoi Cheuk; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The skin forms a critical barrier against the external environment and is therefore frequently challenged by infections and subjected to immune-mediated diseases as well as malignancies. The Tissue-Resident Memory T (TRM) cell is a subset of T cells that resides at sites of previous infection in the skin and other epithelial tissues. READ MORE

  7. 25. Compartmentalisation of the immune response in human skin : cross-talk between dendritic cells and T cells in healthy conditions and in psoriasis

    Author : Elisa Martini; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Human skin is highly compartmentalised and distinct subsets of dendritic cells (DCs) and T cells reside in epidermis and dermis. Alterations in the composition of DCs and T cells have been observed in psoriasis, a common cytokine-driven focal inflammatory skin disease. READ MORE