Search for dissertations about: "tnf alpha in rheumatoid arthritis"
Showing result 1 - 5 of 24 swedish dissertations containing the words tnf alpha in rheumatoid arthritis.
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1. Disease activity in rheumatoid arthritis : Studies in interleukin-6, tumour necrosis factor alpha, monocyte activity, acute phase markers, glucocorticoids, and disability
Abstract : In the present studies, aspects of some disease activity measures in rheumatoid arthritis (RA) have been investigated, including the effect of glucocorticoids on this activity. In RA, serum interleukin(IL)-6 levels were elevated and were shown to have a circadian rhythm, with peak levels in the morning, declining towards low or normal levels in the afternoon and evening. READ MORE
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2. Cytokines in rheumatoid arthritis
Abstract : Rheumatoid arthritis (RA) is a chronic systemic disease characterised by inflammation in several joints. Cytokines appear to be important as both disease promoting and disease- suppressing mediators in the disease. READ MORE
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3. Neuropeptides and neurotrophins in arthritis : studies on the human and mouse knee joint
Abstract : Neuropeptides, such as substance P (SP) and bombesin/gastrin-releasing peptide (BN/GRP), and neurotrophins are involved in neuro-immunomodulatory processes and have marked trophic, growth-promoting and inflammation-modulating properties. The impact of these modulators in rheumatoid arthritis (RA) is, however, unclear. READ MORE
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4. The involvement of the TNF-alpha system in skeletal muscle in response to marked overuse
Abstract : Painful conditions having the origin within the musculoskeletal system is a common cause for people to seek medical care. Between 20-40% of all visits to the primal care in Sweden are coupled to pain from the musculoskeletal system. Muscle pain and impaired muscle function can be caused by muscles being repetitively overused and/or via heavy load. READ MORE
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5. Functional studies of T-cells in rheumatoid arthritis
Abstract : Rheumatoid arthritis (RA) is a systemic inflammatory disease with autoimmune features primarily affecting the joints. The etiology of RA is largely unknown but involvement of the immune system in the disease process is evident from the infiltration of leukocytes into the joint, and by the production of proinflammatory cytokines, chemokines and proteases, mainly by macrophages. READ MORE